Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Psoriasis is widely regarded as a multifactorial condition which is caused by the interaction
between inherited susceptibility alleles and environmental triggers. In the last decade …

To gain further insight into the genetic architecture of psoriasis, we conducted a meta-
analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up
to 30% of people with PsV eventually develop psoriatic arthritis (PsA), an inflammatory …

Psoriasis is a common, chronic inflammatory skin disorder that occurs worldwide. However,
epidemiological, clinical, and therapeutic data pertaining to psoriasis in non-Caucasian …

Psoriasis and PsA are immune-mediated diseases with a strong genetic component. More
than 20 new loci have been recently linked to these diseases. However, interactions …

Background Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies
suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is …

Over the past 2 decades, considerable progress has been made to further elucidate the
complex pathogenesis of psoriasis, facilitating the development of a new armamentarium of …

Psoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors
regulating gene expression play a key role. In the “genomic era”, genome-wide association …