Crystallisation processes have evolved to practical methods that allow isolation of an
enantiopure product in high yield. Viedma ripening in particular enables access to …

Conglomerate crystallization is the spontaneous generation of individually enantioenriched
crystals from a nonenantioenriched material. This behavior is responsible for spontaneous …

The single-operation deracemization of 3H indolines and tetrahydroquinolines is described.
An asymmetric redox approach was employed, in which a phosphoric acid catalyst, oxidant …

The study of chirogenesis of organic molecules is important to elucidate the origin of the
homochirality of biomolecules on Earth. Here, we have accomplished chiral symmetry …

Obtaining pure enantiomers is crucial since the two enantiomers of chiral compounds can
exhibit vastly different optical, biological, and pharmacological properties. Two mixed …

Viedma ripening is the attrition-induced spontaneous chiral amplification of a conglomerate
crystal mixture. To demonstrate the general nature of this deracemization process, we have …

In this contribution, we report on the facile synthesis of hybrid silica nanoparticles grafted
with helical poly (phenyl isocyanide) s via both “grafting from” and “grafting to” strategies …

Viedma ripening is a deracemization process that has been used to deracemize a range of
chiral molecules. The method has two major requirements: the compound needs to …

Deracemisation reactions occur when a racemic mixture is converted into a nonracemic
mixture by increasing the quantity of one enantiomer at the expense of the other. This …

Amplification of enantiomeric excesses (ee) is routinely observed during chiral crystallization
of conglomerate crystals for which the enantiomers undergo racemization in solution …