Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Efficient bioproduction of 3-hydroxypropionic acid from methanol by a synthetic yeast cell factory

X Wu, P Cai, L Gao, Y Li, L Yao… - … Sustainable Chemistry & …, 2023 - ACS Publications
Methanol is an ideal feedstock for bio-manufacturing chemicals without the dependence of
sugars and the competition of arable lands. We here engineered an industrial yeast Pichia …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Process engineering for microbial production of 3-hydroxypropionic acid

F de Fouchécour, AK Sánchez-Castañeda… - Biotechnology …, 2018 - Elsevier
Due to concerns about the unsustainability and predictable shortage of fossil feedstocks,
research efforts are currently being made to develop new processes for production of …

Biological production of 3-hydroxypropionic acid: an update on the current status

L Matsakas, K Hrůzová, U Rova, P Christakopoulos - Fermentation, 2018 - mdpi.com
The production of high added-value chemicals from renewable resources is a necessity in
our attempts to switch to a more sustainable society. 3-Hydroxypropionic acid (3HP) is a …

Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria

P Zhao, P Tian - World Journal of Microbiology and Biotechnology, 2021 - Springer
Hydroxypropionic acid (3-HP) represents an economically important platform compound
from which a panel of bulk chemicals can be derived. Compared with petroleum-dependent …

Extraction, isolation, and purification of value-added chemicals from lignocellulosic biomass

T Chaturvedi, LSS Hulkko, M Fredsgaard… - Processes, 2022 - mdpi.com
This review covers the operating conditions for extracting top value-added chemicals, such
as levulinic acid, lactic acid, succinic acid, vanillic acid, 3-hydroxypropionic acid, xylitol, 2, 5 …

Design and engineering of whole-cell biocatalytic cascades for the valorization of fatty acids

JW Song, JH Seo, DK Oh, UT Bornscheuer… - Catalysis Science & …, 2020 - pubs.rsc.org
One of the key factors to construct a productive whole-cell biocatalytic cascade may include
the design of the biotransformation pathways, discovery and engineering of the cascade …

Notable improvement of 3-hydroxypropionic acid and 1, 3-propanediol coproduction using modular coculture engineering and pathway rebalancing

Y Zhang, HM Zabed, J Yun, G Zhang… - ACS Sustainable …, 2021 - ACS Publications
Sustainable bioconversion of glycerol into 3-hydroxypropionic acid (3-HP) and 1, 3-
propanediol (1, 3-PDO) is often bottlenecked by the accumulation of a toxic metabolic …