The detrimental effects of drug abuse are apparently not limited to individuals but may also
impact the vulnerability of their progenies to develop addictive behaviours. Epigenetic …

Ethanol-induced behavioral sensitization (EBS) was first described in 1980, approximately
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …

Drug addiction is a chronic neuropsychiatric disorder that escalates from an initial exposure
to drugs of abuse, such as cocaine, cannabis, or heroin, to compulsive drug-seeking and …

Chronic alcohol intake is associated with widespread disruptions in sleep and circadian
rhythms in both human alcoholics and in experimental animals. Recent studies have …

Alcohol use disorder (AUD) is an increasingly prevalent disorder that contributes
significantly to the global burden of disease. According to the incentive sensitization theory …

Background: Alcohol use disorders (abuse and dependence, AUD) are multifactorial
phenomena, depending on the interplay of environmental and genetic variables. Method …

Drug-induced behavioral sensitization in rodents has enhanced our understanding of why
drugs acquire increasing motivational and incentive value. Compared to adults, human …

Adolescent social conditions profoundly affect vulnerability to drug abuse. Preclinical studies
have shown that preventing social interactions during adolescence increases the rewarding …

Rearing in crowded conditions is a psychosocial stressor that affects biological functions.
The effects of continuous crowding for many days have been studied, but those of crowding …

Behavioral sensitization, defined as a progressive increase in the locomotor stimulant effects
elicited by repeated exposure to drugs of abuse, has been used as an animal model for drug …