The vertebrate retina first evolved some 500 million years ago in ancestral marine
chordates. Since then, the eyes of different species have been tuned to best support their …

In the retina, photoreceptors pass visual information to interneurons, which process it and
pass it to retinal ganglion cells (RGCs). Axons of RGCs then travel through the optic nerve …

Neuronal types in the central nervous system differ dramatically in their resilience to injury or
other insults. Here we studied the selective resilience of mouse retinal ganglion cells …

Classification and characterization of neuronal types are critical for understanding their
function and dysfunction. Neuronal classification schemes typically rely on measurements of …

In the vertebrate visual system, all output of the retina is carried by retinal ganglion cells.
Each type encodes distinct visual features in parallel for transmission to the brain. How …

Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

Retinal bipolar cells are the first'projection neurons' of the vertebrate visual system—all of
the information needed for vision is relayed by this intraretinal connection. Each of the at …

Injured neurons in the adult mammalian central nervous system often die and seldom
regenerate axons. To uncover transcriptional pathways that could ameliorate these …

The superior colliculus is a midbrain structure that plays important roles in visually guided
behaviors in mammals. Neurons in the superior colliculus receive inputs from retinal …

BigNeuron is an open community bench-testing platform with the goal of setting open
standards for accurate and fast automatic neuron tracing. We gathered a diverse set of …