[HTML][HTML] Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

MA Khan, M Tania, S Fu, J Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this
review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of …

The Immunomodulatory Effect of Nigella sativa

K Ciesielska-Figlon, K Wojciechowicz, A Wardowska… - Antioxidants, 2023 - mdpi.com
Background: For thousands of years till nowadays, Nigella sativa (NS) has served as a
common spice and food preservative. Its seed extracts, seed oil, and essential oil in …

Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation

K Chaieb, B Kouidhi, H Jrah, K Mahdouani… - … and alternative medicine, 2011 - Springer
Background Thymoquinone is an active principle of Nigella sativa seed known as" Habbah
Al-Sauda" in Arabic countries and" Sinouj" in Tunisia. Bacterial biofilms tend to exhibit …

[HTML][HTML] Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition

MA Khan, M Tania, C Wei, Z Mei, S Fu, J Cheng, J Xu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Proteins that promote epithelial to mesenchymal transition (EMT) are associated with cancer
metastasis. Inhibition of EMT regulators may be a promising approach in cancer therapy. In …

[HTML][HTML] Physicochemical Characteristics of Nigella Seed (Nigella sativa L.) Oil as Affected by Different Extraction Methods

A Khoddami, HM Ghazali, A Yassoralipour… - Journal of the American …, 2011 - Springer
The physicochemical properties of crude Nigella seed (Nigella sativa L.) oil which was
extracted using Soxhlet, Modified Bligh–Dyer and Hexane extraction methods were …

Thymoquinone inhibits the migration and invasive characteristics of cervical cancer cells SiHa and CaSki in vitro by targeting epithelial to mesenchymal transition …

J Li, MA Khan, C Wei, J Cheng, H Chen, L Yang, I Ijaz… - Molecules, 2017 - mdpi.com
Cervical cancer is one of the most common gynecological malignant tumors worldwide, for
which chemotherapeutic strategies are limited due to their non-specific cytotoxicity and drug …

Nigella sativa: Holy Herb of the Middle East

E Yarnell, K Abascal - Alternative and complementary Therapies, 2011 - liebertpub.com
Nigella sativa (black seed or black cumin) originated from the Mediterranean region and has
been used in cultures in that area since time immemorial. The well-named herb has jetblack …

In vitro prospective effects of various traditional herbal coffees consumed in Anatolia linked to neurodegeneration

N Sekeroglu, FS Senol, IE Orhan, AR Gulpinar… - Food research …, 2012 - Elsevier
Various herbal coffee varieties are consumed traditionally in Turkey. In the current study, the
ethanol extracts of the coffee and seed samples obtained from Gundelia tournefortii (tumble …

A comparative study of black cumin seed (Nigella sativa L.) oils extracted with supercritical fluids and conventional extraction methods

Z Albakry, E Karrar, IA Mohamed Ahmed, AA Ali… - Journal of Food …, 2023 - Springer
Black cumin (Nigella sativa L.) seed oil is of high nutritional and pharmaceutical quality as it
is rich in polyunsaturated fatty acids and bioactive components, which are greatly affected by …

Pharmaceutical significance of Nigella sativa L., a wonder herb

I Ara, M Maqbool, G Fekadu, TA Hajam… - Journal of Applied …, 2020 - japsr.in
Abstract Nigella sativa L.(Family: Ranunculaceae; commonly known as black cumin) is an
annual herb. N. sativa is cultivated and distributed all over India, especially in Punjab …