Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Coronaviruses are adept at evading host antiviral pathways induced by viral double-
stranded RNA, including interferon (IFN) signaling, oligoadenylate synthetase–ribonuclease …

Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts
of infarcted myocardium and beat in synchrony with the heart, but in some settings cause …

Poly (N-isopropylacrylamide)(PNIPAM)-based thermosensitive hydrogels demonstrate great
potential in biomedical applications. However, they have inherent drawbacks such as low …

Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …

It is challenging to balance high biocompability with good mechanical–electrical sensing
performance, especially when triggering inflammatory stress response after in vivo …

Background: Advancing structural and functional maturation of stem cell–derived
cardiomyocytes remains a key challenge for applications in disease modeling, drug …

Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes
(hiPSC-CMs) for drug development and disease modeling studies, methods to generate …