Multiscale modeling of the neuromuscular system: coupling neurophysiology and skeletal muscle mechanics

O Röhrle, UŞ Yavuz, T Klotz, F Negro… - … : Systems Biology and …, 2019 - Wiley Online Library
Mathematical models and computer simulations have the great potential to substantially
increase our understanding of the biophysical behavior of the neuromuscular system. This …

On the anisotropy of skeletal muscle tissue under compression

M Böl, AE Ehret, K Leichsenring, C Weichert, R Kruse - Acta biomaterialia, 2014 - Elsevier
This paper deals with the role of the muscle fibres and extracellular matrix (ECM)
components when muscle tissue is subjected to compressive loads. To this end, dissected …

[HTML][HTML] Correlating the microstructural architecture and macrostructural behaviour of the brain

M Hoppstädter, D Püllmann, R Seydewitz, E Kuhl… - Acta Biomaterialia, 2022 - Elsevier
The computational simulation of pathological conditions and surgical procedures, for
example the removal of cancerous tissue, can contribute crucially to the future of medicine …

A structural model of passive skeletal muscle shows two reinforcement processes in resisting deformation

J Gindre, M Takaza, KM Moerman, CK Simms - Journal of the mechanical …, 2013 - Elsevier
Passive skeletal muscle derives its structural response from the combination of the titin
filaments in the muscle fibres, the collagen fibres in the connective tissue and …

[HTML][HTML] The energy of muscle contraction. I. Tissue force and deformation during fixed-end contractions

JM Wakeling, SA Ross, DS Ryan, B Bolsterlee… - Frontiers in …, 2020 - frontiersin.org
During contraction the energy of muscle tissue increases due to energy from the hydrolysis
of ATP. This energy is distributed across the tissue as strain-energy potentials in the …

Muscle force depends on the amount of transversal muscle loading

T Siebert, O Till, N Stutzig, M Günther… - Journal of biomechanics, 2014 - Elsevier
Skeletal muscles are embedded in an environment of other muscles, connective tissue, and
bones, which may transfer transversal forces to the muscle tissue, thereby compressing it. In …

Three-dimensional muscle architecture and comprehensive dynamic properties of rabbit gastrocnemius, plantaris and soleus: input for simulation studies

T Siebert, K Leichsenring, C Rode, C Wick, N Stutzig… - PLoS one, 2015 - journals.plos.org
The vastly increasing number of neuro-muscular simulation studies (with increasing
numbers of muscles used per simulation) is in sharp contrast to a narrow database of …

The in vitro passive elastic response of chicken pectoralis muscle to applied tensile and compressive deformation

M Mohammadkhah, P Murphy, CK Simms - Journal of the mechanical …, 2016 - Elsevier
The mechanics of passive skeletal muscle are important in impact biomechanics, surgical
simulation, and rehabilitation engineering. Existing data from porcine tissue has shown a …

[HTML][HTML] On multiscale tension-compression asymmetry in skeletal muscle

M Böl, S Kohn, K Leichsenring, E Morales-Orcajo… - Acta Biomaterialia, 2022 - Elsevier
Skeletal muscle tissue shows a clear asymmetry with regard to the passive stresses under
tensile and compressive deformation, referred to as tension-compression asymmetry (TCA) …

Mechanical and microstructural changes of skeletal muscle following immobilization and/or stroke

N Jalal, JM Gracies, M Zidi - Biomechanics and modeling in …, 2020 - Springer
Patient management following a stroke currently represents a medical challenge. The
presented study investigates the effect of immobilization on skeletal muscles in short …