Prebiotic peptides: Molecular hubs in the origin of life
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
Hierarchical nanomaterials assembled from peptoids and other sequence-defined synthetic polymers
In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …
plays an essential role in the construction of functional biomaterials. To develop synthetic …
[HTML][HTML] Ultrashort peptide self-assembly: front-runners to transport drug and gene cargos
The translational therapies to promote interaction between cell and signal come with
stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet …
stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet …
[HTML][HTML] Unnatural helical peptidic foldamers as protein segment mimics
P Sang, J Cai - Chemical Society Reviews, 2023 - pubs.rsc.org
Unnatural helical peptidic foldamers have attracted considerable attention owing to their
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
Supramolecular peptide hydrogel-based soft neural interface augments brain signals through a three-dimensional electrical network
Recording neural activity from the living brain is of great interest in neuroscience for
interpreting cognitive processing or neurological disorders. Despite recent advances in …
interpreting cognitive processing or neurological disorders. Despite recent advances in …
[HTML][HTML] The diverse world of foldamers: endless possibilities of self-assembly
S Rinaldi - Molecules, 2020 - mdpi.com
Different classes of foldamers, which are synthetic oligomers that adopt well-defined
conformations in solution, have been the subject of extensive studies devoted to the …
conformations in solution, have been the subject of extensive studies devoted to the …
[HTML][HTML] Self-assembling peptide biomaterials: Insights from spontaneous and enhanced sampling molecular dynamics simulations
BJ Williams-Noonan, A Kamboukos… - Chemical Physics …, 2023 - pubs.aip.org
Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …
A self-assembling β-peptide hydrogel for neural tissue engineering
We report a new class of β-peptide based hydrogel for neural tissue engineering. Our β-
peptide forms a network of nanofibres in aqueous solution, resulting in a stable hydrogel at …
peptide forms a network of nanofibres in aqueous solution, resulting in a stable hydrogel at …
[PDF][PDF] Geometrically precise building blocks: the self-assembly of β-peptides
Peptides comprised entirely of β-amino acids, or β-peptides, have attracted substantial
interest over the past 25 years due to their unique structural and chemical characteristics. β …
interest over the past 25 years due to their unique structural and chemical characteristics. β …
From folding to assembly: functional supramolecular architectures of peptides comprised of non‐canonical amino acids
R Misra, S Rudnick‐Glick… - Macromolecular …, 2021 - Wiley Online Library
The engineering of biological molecules is the fundamental concept behind the design of
complex materials with desirable functions. Over the last few decades, peptides and proteins …
complex materials with desirable functions. Over the last few decades, peptides and proteins …