The catechol-O-methyltransferase polymorphism: Relations to the tonic–phasic dopamine hypothesis and neuropsychiatric phenotypes

RM Bilder, J Volavka, HM Lachman… - …, 2004 - nature.com
Diverse phenotypic associations with the catechol-O-methyltransferase (COMT) Val 158 Met
polymorphism have been reported. We suggest that some of the complex effects of this …

Pathophysiology of obsessive–compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology

B Aouizerate, D Guehl, E Cuny, A Rougier… - Progress in …, 2004 - Elsevier
Obsessive–compulsive disorder (OCD) is characterized by repetitive intrusive thoughts and
compulsive time-consuming behaviors classified into three to five distinct symptom …

Orofacial pain prospective evaluation and risk assessment study–the OPPERA study

W Maixner, L Diatchenko, R Dubner, RB Fillingim… - The journal of Pain, 2011 - jpain.org
Temporomandibular disorders (TMD) consist of a heterogeneous family of musculoskeletal
disorders that represent the most common chronic orofacial pain condition. 15, 16, 57 …

Molecular genetics of obsessive–compulsive disorder: a comprehensive meta-analysis of genetic association studies

S Taylor - Molecular psychiatry, 2013 - nature.com
Twin studies indicate that obsessive–compulsive disorder (OCD) is strongly influenced by
additive genetic factors. Yet, molecular genetic association studies have yielded inconsistent …

The genetics of obsessive-compulsive disorder: a review

DL Pauls - Dialogues in clinical neuroscience, 2010 - Taylor & Francis
Obsessive-compulsive disorder (OCD) is a serious psychiatric disorder that affects
approximately 2% of the populations of children and adults. Family aggregation studies …

Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder

PD Arnold, T Sicard, E Burroughs… - Archives of general …, 2006 - jamanetwork.com
Context There is strong evidence from family and twin studies that genetic determinants play
an important role in the etiology of obsessive-compulsive disorder (OCD). In the only …

The role of dopamine in obsessive-compulsive disorder: preclinical and clinical evidence

D Denys, J Zohar, HG Westenberg - J Clin Psychiatry, 2004 - psychiatrist.com
Obsessive-compulsive disorder (OCD) is a frequent and chronic psychiatric disorder that
has been linked closely to the serotonin system mainly because of the antiobsessional …

Assessing the molecular genetics of attention networks

J Fossella, T Sommer, J Fan, Y Wu, JM Swanson… - BMC neuroscience, 2002 - Springer
Background Current efforts to study the genetic underpinnings of higher brain functions have
been lacking appropriate phenotypes to describe cognition. One of the problems is that …

Gender differences in obsessive-compulsive disorder: a literature review

MA Mathis, P Alvarenga, G Funaro… - Brazilian Journal of …, 2011 - SciELO Brasil
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a heterogeneous condition, in
which subtypes have been proposed. Previous studies suggested that gender plays a …

Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder

DE Dickel, J Veenstra-VanderWeele… - Archives of general …, 2006 - jamanetwork.com
Context The first 2 independent linkage studies for obsessive-compulsive disorder (OCD)
identified a region on 9p24 with suggestive evidence for linkage. The glutamate transporter …