[HTML][HTML] Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Oxidant mechanisms in renal injury and disease

BB Ratliff, W Abdulmahdi, R Pawar… - Antioxidants & redox …, 2016 - liebertpub.com
Significance: A common link between all forms of acute and chronic kidney injuries,
regardless of species, is enhanced generation of reactive oxygen species (ROS) and …

[HTML][HTML] Catalytic antioxidants in the kidney

YA Hong, CW Park - Antioxidants, 2021 - mdpi.com
Reactive oxygen species and reactive nitrogen species are highly implicated in kidney
injuries that include acute kidney injury, chronic kidney disease, hypertensive nephropathy …

Role of thymoquinone and ebselen in the prevention of sodium arsenite–induced nephrotoxicity in female rats

AY Al-Brakati, RB Kassab, MS Lokman… - Human & …, 2019 - journals.sagepub.com
The aim of this study is to investigate the protective effects of thymoquinone (TQ) and
ebselen (Eb) on arsenic (As)-induced renal toxicity in female rats. Sodium arsenite was …

Melatonin attenuates contrast‐induced nephropathy in diabetic rats: the role of Interleukin‐33 and oxidative stress

D Onk, OA Onk, K Turkmen, HS Erol… - Mediators of …, 2016 - Wiley Online Library
Background. Inflammation and oxidative stress (OxS) contribute to the pathogenesis of
diabetic kidney disease (DKD) and contrast‐induced nephropathy (CIN). Patients with DKD …

Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines …

CS Kunak, RA Ugan, E Cadirci… - The British Journal of …, 2016 - academic.oup.com
Objective: Contrast media (CM) are a major cause of nephropathy in high-risk patients. The
aim of this study was to examine the effects of carnitine (CAR) in advanced nephrotoxicity …

Selenosteroids-promising hybrid compounds with pleiotropic biological activity: synthesis and biological aspects

I Jastrzebska, PA Grzes… - The Journal of Steroid …, 2021 - Elsevier
It is established that steroid based agents are an example of compounds obtained from
natural patterns and are of great importance due to their application in the prevention and …

The effect of L-carnitine on oxidative stress responses of experimental contrast-induced nephropathy in rats

M Boyacioglu, H Turgut, C Akgullu… - Journal of veterinary …, 2014 - jstage.jst.go.jp
This study was conducted to investigate the prophylactic effects of carnitine against contrast-
induced nephropathy (CIN) and its relation to oxidant/antioxidant status in kidney, liver …

Induction of apoptosis in human multiple myeloma cell lines by ebselen via enhancing the endogenous reactive oxygen species production

L Zhang, L Zhou, J Du, M Li, C Qian… - BioMed Research …, 2014 - Wiley Online Library
Ebselen a selenoorganic compound showing glutathione peroxidase like activity is an anti‐
inflammatory and antioxidative agent. Its cytoprotective activity has been investigated in …

Neuroprotective effects of ebselen in traumatic brain injury model: involvement of nitric oxide and p38 mitogen‐activated protein kinase signalling pathway

L Wei, Y Zhang, C Yang, Q Wang… - Clinical and …, 2014 - Wiley Online Library
Previous investigations have found that ebselen is able to treat neurodegenerative diseases
caused by radical and acute total cerebral ischaemia. The aim of the present study was to …