Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Structure–activity relationship of cationic surfactants as antimicrobial agents

C Zhou, Y Wang - Current Opinion in Colloid & Interface Science, 2020 - Elsevier
Cationic surfactants are widely used as antimicrobial agents in various fields. However, the
widespread use of cationic surfactants has caused huge accumulation in environment …

Advances in development of antimicrobial peptidomimetics as potential drugs

N Molchanova, PR Hansen, H Franzyk - Molecules, 2017 - mdpi.com
The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …

Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry

C Vicente-Garcia, I Colomer - Nature Reviews Chemistry, 2023 - nature.com
Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C
or N terminus of peptides. Their self-assembly—into micelles, vesicles, nanotubes, fibres or …

Amino acid–based surfactants: New antimicrobial agents

A Pinazo, MA Manresa, AM Marques, M Bustelo… - Advances in colloid and …, 2016 - Elsevier
The rapid increase of drug resistant bacteria makes necessary the development of new
antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising …

New progress in azole compounds as antimicrobial agents

HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents

S Ramesh, T Govender, HG Kruger… - Journal of Peptide …, 2016 - Wiley Online Library
The emergence of multidrug resistant bacteria has a direct impact on global public health
because of the reduced potency of existing antibiotics against pathogens. Hence, there is a …

Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity

M Ahn, P Gunasekaran, G Rajasekaran, EY Kim… - European journal of …, 2017 - Elsevier
In this study, we report on the first chemical synthesis of ultra-short pyrazole-arginine based
antimicrobial peptidomimetics derived from the newly synthesized N-alkyl/aryl pyrazole …

Evaluation of peptoid mimics of short, lipophilic peptide antimicrobials

RM Green, KL Bicker - International journal of antimicrobial agents, 2020 - Elsevier
Introduction Antimicrobial peptides are proving to be promising lead compounds for
therapeutics. The major disadvantage of antimicrobial peptides is their proteolytic instability …

Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin

T Liu, N Zhu, C Zhong, Y Zhu, S Gou, L Chang… - European Journal of …, 2020 - Elsevier
With the increment of drug-resistant bacteria and the slow development of novel antibiotics,
antimicrobial peptides have gained increasing attention as a potential antibiotic alternative …