[HTML][HTML] Astrocyte heterogeneity: impact to brain aging and disease
I Matias, J Morgado, FCA Gomes - Frontiers in aging neuroscience, 2019 - frontiersin.org
Astrocytes, one of the largest glial cell population in the central nervous system (CNS), play
a key function in several events of brain development and function, such as synapse …
a key function in several events of brain development and function, such as synapse …
Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage
H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
[HTML][HTML] Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Loss of lamin‐B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
I Matias, LP Diniz, IV Damico, APB Araujo… - Aging cell, 2022 - Wiley Online Library
The increase in senescent cells in tissues, including the brain, is a general feature of normal
aging and age‐related pathologies. Senescent cells exhibit a specific phenotype, which …
aging and age‐related pathologies. Senescent cells exhibit a specific phenotype, which …
[HTML][HTML] Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis
ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
Flavonoids as therapeutic agents in Alzheimer's and Parkinson's diseases: a systematic review of preclinical evidences
RB de Andrade Teles, TC Diniz… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's and Parkinson's diseases are considered the most common neurodegenerative
disorders, representing a major focus of neuroscience research to understanding the …
disorders, representing a major focus of neuroscience research to understanding the …
[HTML][HTML] The benefits of hesperidin in central nervous system disorders, based on the neuroprotective effect
X Li, W Huang, R Tan, C Xu, X Chen, S Li, Y Liu… - Biomedicine & …, 2023 - Elsevier
Disorders of central nervous system (CNS) disorders are considered serious health issues.
The most common CNS diseases include neurodegenerative diseases, mental disorders …
The most common CNS diseases include neurodegenerative diseases, mental disorders …
[HTML][HTML] Plant-derived antioxidants protect the nervous system from aging by inhibiting oxidative stress
X Cui, Q Lin, Y Liang - Frontiers in aging neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) has become a major disease contributing to human death and is
thought to be closely related to the aging process. The rich antioxidant substances in plants …
thought to be closely related to the aging process. The rich antioxidant substances in plants …
Astrocytes and the TGF-β1 pathway in the healthy and diseased brain: a double-edged sword
LP Diniz, I Matias, M Siqueira, J Stipursky… - Molecular …, 2019 - Springer
Transforming growth factor betas (TGF-βs) are known as multifunctional growth factors that
participate in the regulation of key events of development, disease, and tissue repair. In the …
participate in the regulation of key events of development, disease, and tissue repair. In the …
[HTML][HTML] Contribution of Müller cells in the diabetic retinopathy development: Focus on oxidative stress and inflammation
R Carpi-Santos, RA de Melo Reis, FCA Gomes… - Antioxidants, 2022 - mdpi.com
Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …