Schistosomiasis and herpes diseases represent serious issues to the healthcare systems,
infecting a large number of people worldwide, mainly in developing countries. Arctium lappa …

Abstract (±)-Licarin A (1) was obtained by oxidative coupling, and its enantiomers,(−)-licarin
A (2) and (+)-licarin A (3), were resolved by chiral HPLC. Schistosomicidal and trypanocidal …

Seven tetrahydrofuran lignans, isolated from Nectandra megapotamica (Lauraceae), were
evaluated for their in vitro antileishmanial and antimalarial activities. Among the evaluated …

Na busca de novos agentes leishmanicidas, avaliamos em culturas de promastigotas de
Leishmania amazonensis o efeito dos extratos hidroalcoólicos das folhas de Tephrosia …

The chemotherapy of schistosomiasis relies on the use of praziquantel. However, concerns
over drug resistance have encouraged the search for new drug leads. This paper is the first …

Leishmanicide potential of Calophyllum brasiliense leaves on promastigote and amastigote
of Leishmania (Leishmania) amazonensis is evaluated. The LD50 of dichloromethane …

Leishmaniasis is an infectious disease that affects both animals and humans, caused by
flagellated parasites belonging to the genus Leishmania. The disease is estimated to reach …

We describe the microwave-assisted synthesis of ten 3-methoxycarbonyl-γ-butyrolactone
derivatives and evaluate their in vitro antileishmanial activity against promastigote forms of …

The trypanocidal activity of racemic mixtures of cis-and trans-methylpluviatolides was
evaluated in vitro against trypomastigote forms of two strains of Trypanosoma cruzi, and in …

(±)-Licarin A (1), a neolignan obtained by the oxidative coupling reaction of isoeugenol, had
in this study its enantiomers resolved. A novel, quick and efficient enantiomeric resolution of …