CD40 is a TNF receptor superfamily member expressed on both immune and non-immune
cells. Interactions between B cell-expressed CD40 and its binding partner, CD40L …

Sjögren's syndrome (SS) is a prototype autoimmune disease characterized by oral and
ocular mucosal dryness following chronic inflammation of salivary and lachrymal glands …

Plasmacytoid dendritic cells (pDCs) have long been implicated in the pathogenesis of lupus.
However, this conclusion has been largely based on a correlative link between the copious …

Nearly one trillion platelets circulate in the blood to monitor and preserve the integrity of the
vasculature. However, haemostasis is not their only function. Platelets are also potent …

Objective Primary Sjögren's syndrome (pSS) is characterised by chronic hyperactivation of B
lymphocytes. Salivary gland epithelial cells (SGECs) could play a role in promoting B …

CD40 is a tumor necrosis factor receptor superfamily member expressed by immune and
non-immune cells. CD40: CD154 interactions mediate T-dependent B cell responses and …

CD40 ligand (CD40L) stimulation induces proinflammatory and immunomodulatory activity
in monocytes. Here, we report on the effects of the steroid hormone 1α, 25-dihydroxyvitamin …

Introduction Cell stimulation leads to the shedding of phosphatidylserine (PS)-rich
microparticles (MPs). Because autoimmune diseases (AIDs) are characterized by cell …

Eosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad
spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in …

RA is characterized by a systemic inflammatory state, in which immune cells and soluble
mediators play a crucial role. These inflammatory processes resemble those in other chronic …