N-Heterocyclic carbene complexes in C–H activation reactions

Q Zhao, G Meng, SP Nolan, M Szostak - Chemical reviews, 2020 - ACS Publications
In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

Recent advances in the anticancer applications of benzimidazole derivatives

M Mavvaji, S Akkoc - ChemistrySelect, 2023 - Wiley Online Library
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …

Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag (I) NHC coordination compounds

A Kazancı, Y Gök, R Kaya, A Aktaş, P Taslimi, İ Gülçin - Polyhedron, 2021 - Elsevier
This study contains the synthesis of N-phthalimidomethyl-substituted NHC precursors and
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …

Derivatives of 1‐(2‐(Piperidin‐1‐yl)ethyl)‐1H‐benzo[d]imidazole: Synthesis, Characterization, Determining of Electronic Properties and Cytotoxicity Studies

S Akkoç - ChemistrySelect, 2019 - Wiley Online Library
A series of heterocyclic compounds were synthesized and fully characterized. The geometry
optimization was carried out using the Density Functional Theory (DFT) method and the …

Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties

S Bal, R Kaya, Y Gök, P Taslimi, A Aktaş, M Karaman… - Bioorganic …, 2020 - Elsevier
In this work, structures of different imidazolium compounds were designed and synthesized.
These compounds were synthesized from 2-methylimidazole and alkyl/aryl halides. Their …

New compounds based on a benzimidazole nucleus: synthesis, characterization and cytotoxic activity against breast and colon cancer cell lines

S Akkoc, V Kayser, İÖ İlhan, DE Hibbs, Y Gök… - Journal of …, 2017 - Elsevier
Benzimidazolium salts and their Pyridine Enhanced Precatalyst Preparation Stabilization
and I nitiation (PEPPSI) palladium N-heterocyclic carbene (Pd-NHC) based complexes have …

Recent advances in benzimidazole based NHC‐metal complex catalysed cross‐coupling reactions

PP Nair, A Jayaraj, CA Swamy P - ChemistrySelect, 2022 - Wiley Online Library
In recent years, there has been a substantial increase in the development of efficient,
environmentally compatible and cost‐effective catalysts as a replacement for conventional …

Recent advances in the application of heterogeneous catalysts for the synthesis of benzimidazole derivatives

M Mavvaji, S Akkoc - Coordination Chemistry Reviews, 2024 - Elsevier
Benzimidazole derivatives have exhibited marvelous utility due to their widespread
pharmaceutical features, including anti-fungal, anti-viral, anti-bacterial, anti-cancer, anti …

Design, Synthesis, and In Silico and In Vitro Cytotoxic Activities of Novel Isoniazid–Hydrazone Analogues Linked to Fluorinated Sulfonate Esters

E Başaran, G Tür, S Akkoc, T Taskin-Tok - ACS omega, 2024 - ACS Publications
Cancer is a life-threatening disease, and significant efforts are still being made to treat it. In
this study, we synthesized and characterized novel hybrid molecules (10–18) containing …

In vitro cytotoxic activities of new silver and PEPPSI palladium N-heterocyclic carbene complexes derived from benzimidazolium salts

S Akkoc, İÖ İlhan, Y Gök, PJ Upadhyay… - Inorganica Chimica Acta, 2016 - Elsevier
Abstract New benzimidazolium salts (2, 3) and their silver (4, 5) and palladium (6, 7) N-
heterocyclic carbene (Ag-and Pd-NHC) complexes were designed, synthesized and …