Organoid technology is a state‐of‐the‐art cell culture tool that has revolutionized study of
development, regeneration, and diseases. Human liver organoids (HLOs) are now derived …

During foetal life, the liver plays the important roles of connection and transient
hematopoietic function. Foetal liver cells develop in an environment called a hematopoietic …

Background: Biliary tract cancers (BTC) are relatively rare malignant tumours with poor
prognosis. It is known from other solid neoplasms that antitumour inflammatory response …

Liver transplantation is the only existing modality for treating decompensated liver cirrhosis.
Several factors, such as nonavailability of donors, combined with operative risks …

Accumulating evidence suggests that cancer stem cells (CSC) play an important role in
tumorigenicity. Epithelial cell adhesion molecule (EpCAM) is one of the markers that …

The liver possesses an extraordinary ability to regenerate after injury. Hepatocyte-driven
liver regeneration is the default pathway in response to mild-to-moderate acute liver …

Our understanding of human hepatocellular carcinoma (HCC) development and
progression has been hampered by the lack of in vivo models. We performed a genetic …

Fetal hepatocytes have a high regenerative capacity. The aim of the study was to assess
treatment safety and clinical efficacy of human fetal liver cell transplantation through splenic …

Background & Aims Human biliary tree stem/progenitor cells (hBTSCs) are multipotent
epithelial stem cells, easily obtained from the biliary tree, with the potential for regenerative …

Liver transplantation is the standard care for many end-stage liver diseases. However, donor
organs are scarce and some people succumb to liver failure before a donor is found. Liver …