Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?

WJAJ Hendriks, RTP van Cruchten… - Frontiers in Cell and …, 2023 - frontiersin.org
Protein tyrosine phosphatases, together with protein tyrosine kinases, control many
molecular signaling steps that control life at cellular and organismal levels. Impairing …

A retrospective analysis of phosphatase catalytic subunit gene variants in patients with rare disorders identifies novel candidate neurodevelopmental disease genes

E Lyulcheva-Bennett… - Frontiers in Cell and …, 2023 - frontiersin.org
Rare genetic disorders represent some of the most severe and life-limiting conditions that
constitute a considerable burden on global healthcare systems and societies. Most …

Progress in the mechanism of neuronal surface P antigen modulating hippocampal function and implications for autoimmune brain disease

F Barake, M Bravo-Zehnder… - Current Opinion in …, 2022 - journals.lww.com
NSPA function is crucial in memory processes controlling the stability of NMDAR at PSD
through the ubiquitination of PTPMEG/PTPN4 and also through AHN. As anti-P …