Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …

Abdominal aortic aneurysm has a high heritability and often co-occurs with other
cardiometabolic disorders, suggesting shared genetic susceptibility. We investigate this …

Autophagy is a well-conserved biological process that maintains homeostasis. Accumulating
evidence has revealed that autophagy plays an important role in various cardiovascular …

An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall
characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and …

There is increasing evidence for enhanced oxidative stress in the vascular wall of abdominal
aortic aneurysms (AAA). Mitochondrial damage and dysfunction are hypothesized to be …

Background N6-methyladenosine (m6A) is found in almost all nuclear RNAs of eukaryotes,
playing an important and diverse role in many biological processes. Nonetheless, the roles …

MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) is a human
paracaspase protein with proteolytic activity via its caspase-like domain. The …

BACKGROUND: Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular
condition, but approved medical therapies to prevent AAA progression and rupture are …

Background. Ferroptosis is a new form of cell death, which is closely related to the
occurrence of many diseases. Our work focused on the mechanism by which HMGB2 …

Abdominal aortic aneurysm (AAA), an extremely dangerous vascular disease with high
mortality, causes massive internal bleeding due to aneurysm rupture. To boost the research …