Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Drosophila olfaction: past, present and future

R Benton - Proceedings of the Royal Society B, 2022 - royalsocietypublishing.org
Among the many wonders of nature, the sense of smell of the fly Drosophila melanogaster
might seem, at first glance, of esoteric interest. Nevertheless, for over a century, the 'nose'of …

[PDF][PDF] A complete electron microscopy volume of the brain of adult Drosophila melanogaster

Z Zheng, JS Lauritzen, E Perlman, CG Robinson… - Cell, 2018 - cell.com
Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-
neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only …

Information flow, cell types and stereotypy in a full olfactory connectome

P Schlegel, AS Bates, T Stürner, SR Jagannathan… - Elife, 2021 - elifesciences.org
The hemibrain connectome provides large-scale connectivity and morphology information
for the majority of the central brain of Drosophila melanogaster. Using this data set, we …

Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body

MJ Dolan, S Frechter, AS Bates, C Dan, P Huoviala… - Elife, 2019 - elifesciences.org
Animals exhibit innate behaviours to a variety of sensory stimuli including olfactory cues. In
Drosophila, one higher olfactory centre, the lateral horn (LH), is implicated in innate …

The wiring diagram of a glomerular olfactory system

ME Berck, A Khandelwal, L Claus, L Hernandez-Nunez… - Elife, 2016 - elifesciences.org
The sense of smell enables animals to react to long-distance cues according to learned and
innate valences. Here, we have mapped with electron microscopy the complete wiring …

[PDF][PDF] Elucidating the neuronal architecture of olfactory glomeruli in the Drosophila antennal lobe

V Grabe, A Baschwitz, HKM Dweck, S Lavista-Llanos… - Cell reports, 2016 - cell.com
Olfactory glomeruli are morphologically conserved spherical compartments of the olfactory
system, distinguishable solely by their chemosensory repertoire, anatomical position, and …

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

CN McLaughlin, M Brbić, Q Xie, T Li, F Horns… - Elife, 2021 - elifesciences.org
Recognition of environmental cues is essential for the survival of all organisms.
Transcriptional changes occur to enable the generation and function of the neural circuits …

Wiring variations that enable and constrain neural computation in a sensory microcircuit

WF Tobin, RI Wilson, WCA Lee - Elife, 2017 - elifesciences.org
Neural network function can be shaped by varying the strength of synaptic connections. One
way to achieve this is to vary connection structure. To investigate how structural variation …

Organization of the Drosophila larval visual circuit

I Larderet, PMJ Fritsch, N Gendre, GL Neagu-Maier… - Elife, 2017 - elifesciences.org
Visual systems transduce, process and transmit light-dependent environmental cues.
Computation of visual features depends on photoreceptor neuron types (PR) present …