Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes

P Hernández-Vargas, M Muñoz… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Successful embryo implantation is a complex process that requires the
coordination of a series of events, involving both the embryo and the maternal endometrium …

Extracellular vesicles in embryo implantation and disorders of the endometrium

A Mishra, N Ashary, R Sharma… - American Journal of …, 2021 - Wiley Online Library
Implantation of the embryo is a rate‐limiting step for a successful pregnancy, and it requires
an intricate crosstalk between the embryo and the endometrium. Extracellular vesicles (EVs) …

Proteomic profiling of human uterine extracellular vesicles reveal dynamic regulation of key players of embryo implantation and fertility during menstrual cycle

A Rai, QH Poh, M Fatmous, H Fang, S Gurung… - …, 2021 - Wiley Online Library
Endometrial extracellular vesicles (EVs) are emerging as important players in reproductive
biology. However, how their proteome is regulated throughout the menstrual cycle is not …

Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure

C von Grothusen, C Frisendahl, V Modhukur… - Human …, 2022 - academic.oup.com
STUDY QUESTION Is the composition of microRNAs (miRNAs) in uterine fluid (UF) of
women with recurrent implantation failure (RIF) different from that of healthy fertile women …

Sperm interactions with the female reproductive tract: a key for successful fertilization in mammals

M Saint-Dizier, C Mahe, K Reynaud, G Tsikis… - Molecular and Cellular …, 2020 - Elsevier
Sperm migration through the female genital tract is not a quiet journey. Uterine contractions
quickly operate a drastic selection, leading to a very restrictive number of sperm reaching …

[HTML][HTML] Aggregation-induced emission dots assisted non-invasive fluorescence hysterography in near-infrared IIb window

X Yu, Y Ying, Z Feng, J Qi, J Zheng, Y Zhang, J Liu… - Nano Today, 2021 - Elsevier
Uterine diseases seriously threaten the physical and mental health of women. The main
principle, when clinicians adopt examinations, is to achieve efficient diagnosis without …

Extracellular vesicles as a potential diagnostic tool in assisted reproduction

E Giacomini, S Makieva, V Murdica… - Current Opinion in …, 2020 - journals.lww.com
Accumulated knowledge on extracellular vesicles deriving from endometrium, follicular fluid,
embryos or male reproductive system may be translated to clinical practice to inform …

Extracellular vesicle research in reproductive science: Paving the way for clinical achievements

E Aleksejeva, N Zarovni, K Dissanayake… - Biology of …, 2022 - academic.oup.com
Mammalian conception involves a multitude of reciprocal interactions via a molecular
dialogue between mother and conceptus. Extracellular vesicles (EVs) are secreted …

The role of extracellular vesicles in endometrial receptivity and their potential in reproductive therapeutics and diagnosis

AR Hart, NLA Khan, K Godakumara, K Dissanayake… - Reproductive …, 2022 - Elsevier
abstract Extracellular vesicles (EVs) are small, nanometre sized, membrane-enclosed
structures released by cells and are thought to be crucial in cellular communication. The …

Altered microRNA profiles of extracellular vesicles secreted by endometrial cells from women with recurrent implantation failure

C Liu, M Wang, H Zhang, C Sui - Reproductive Sciences, 2021 - Springer
Recurrent implantation failure (RIF) is characterized by repeated embryo transfers without
pregnancy. To date, the etiology of RIF remains poorly understood. Accumulating evidence …