Medicinal chemistry is a science applied to the search and discovery of new therapeutic
agents for the treatment of various diseases. Therefore, promising structures have been …

Seven membered heterocyclic Azepine and its derivatives have great pharmacological and
therapeutic implications. In this review, the literature of the last fifty years has been exploited …

This work describes about the synthesis and evaluation of substituted benzofuran
piperazines as potential anticancer agents. The synthesized candidates have been …

Introduction Piperazine is a structural element present in drugs belonging to various
chemical classes and used for numerous different therapeutic applications; it has been …

Piperazine, a nitrogen-containing heterocyclic has acquired an inimitable position in
medicinal chemistry because of its versatile structure, which has fascinated researchers to …

Podophyllotoxin is a naturally occurring cyclolignan isolated from rhizomes of Podophyllum
sp. In the clinic, it is used mainly as an antiviral; however, its antitumor activity is even more …

In nature, N‐heterocyclic compounds and their derivatives are abundant. They serve as the
building blocks of many biological entities, such as enzymes, alkaloids, hormones …

A metal-free multicomponent synthetic route for the diverse preparation of dithiocarbamate-
containing piperazine derivatives was developed through the C–N bond cleavage of …

Piperazine (PIP) is a pharmaceutically acceptable molecule and a good co-conformer in
crystallographic engineering. Most of the non-steroidal anti-inflammatory drugs (NSAIDs) …

Piperazine is a six-membered heterocyclic ring with two nitrogen atoms at positions one and
four. This piperazine moiety can be present in a slew of well-known medicines that have …