Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Influence of the bioactive diet components on the gene expression regulation

J Mierziak, K Kostyn, A Boba, M Czemplik, A Kulma… - Nutrients, 2021 - mdpi.com
Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food
constituents, which can transfer information from the external environment and influence …

Transcriptomic characterization of cow, donkey and goat milk extracellular vesicles reveals their anti-inflammatory and immunomodulatory potential

S Mecocci, D Pietrucci, M Milanesi, L Pascucci… - International journal of …, 2021 - mdpi.com
Milk extracellular vesicles (mEVs) seem to be one of the main maternal messages delivery
systems. Extracellular vesicles (EVs) are micro/nano-sized membrane-bound structures …

Breast milk microRNAs: Potential players in oral tolerance development

E Ahlberg, A Al-Kaabawi, R Thune… - Frontiers in …, 2023 - frontiersin.org
Breast milk is an essential source of nutrition and hydration for the infant. In addition, this
highly complex biological fluid contains numerous immunologically active factors such as …

Levels of breast milk microRNAs and other non-coding RNAs are impacted by milk maturity and maternal diet

SD Hicks, A Confair, K Warren… - Frontiers in immunology, 2022 - frontiersin.org
There is emerging evidence that non-coding RNAs (ncRNAs) within maternal breast milk
(MBM) impart unique metabolic and immunologic effects on developing infants. Most studies …

Extracellular vesicles and their indispensable roles in pathogenesis and treatment of inflammatory bowel disease: A comprehensive review

L Chen, Q Ou, X Kou - Life Sciences, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a global disease with rising incidence worldwide, and
its debilitating symptoms and dissatisfactory therapies have brought heavy burdens for …

[HTML][HTML] Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and growth

L Yeruva, BK Mulakala, D Rajasundaram, S Gonzalez… - Clinical Nutrition, 2023 - Elsevier
Background Maternal diet influences the milk composition, yet little information is available
on the impact of maternal diet on milk miRNAs expression. Further, the association of milk …

Potential epigenetic effects of human milk on infants' neurodevelopment

G Gialeli, O Panagopoulou, G Liosis, T Siahanidou - Nutrients, 2023 - mdpi.com
The advantages of human milk feeding, especially in preterm babies, are well recognized.
Infants' feeding with breast milk lowers the likelihood of developing a diverse range of non …

Gestational diabetes mellitus is associated with altered abundance of exosomal MicroRNAs in human milk

KB Shah, DA Fields, NP Pezant, HK Kharoud… - Clinical …, 2022 - Elsevier
Purpose Human milk (HM) is a unique biological fluid that is enriched with a variety of
factors, including microRNAs (miRNAs) that potentially provide both short-and long-term …

Milk exosomal microRNAs: postnatal promoters of β cell proliferation but potential inducers of β cell de-differentiation in adult life

BC Melnik, G Schmitz - International Journal of Molecular Sciences, 2022 - mdpi.com
Pancreatic β cell expansion and functional maturation during the birth-to-weaning period is
driven by epigenetic programs primarily triggered by growth factors, hormones, and nutrients …