Engineering bacteria as interactive cancer therapies

CR Gurbatri, N Arpaia, T Danino - Science, 2022 - science.org
With increasing evidence that microbes colonize tumors, synthetic biology tools are being
leveraged to repurpose bacteria as tumor-specific delivery systems. These engineered …

[HTML][HTML] Investigation of soft matter nanomechanics by atomic force microscopy and optical tweezers: A comprehensive review

A Magazzù, C Marcuello - Nanomaterials, 2023 - mdpi.com
Soft matter exhibits a multitude of intrinsic physico-chemical attributes. Their mechanical
properties are crucial characteristics to define their performance. In this context, the rigidity of …

Magnetic torque–driven living microrobots for increased tumor infiltration

T Gwisai, N Mirkhani, MG Christiansen, TT Nguyen… - Science Robotics, 2022 - science.org
Biohybrid bacteria–based microrobots are increasingly recognized as promising externally
controllable vehicles for targeted cancer therapy. Magnetic fields in particular have been …

[HTML][HTML] Ultrasound trapping and navigation of microrobots in the mouse brain vasculature

A Del Campo Fonseca, C Glück, J Droux… - Nature …, 2023 - nature.com
The intricate and delicate anatomy of the brain poses significant challenges for the treatment
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …

Micro/nanorobotic swarms: from fundamentals to functionalities

J Law, J Yu, W Tang, Z Gong, X Wang, Y Sun - ACS nano, 2023 - ACS Publications
Swarms, which stem from collective behaviors among individual elements, are commonly
seen in nature. Since two decades ago, scientists have been attempting to understand the …

[HTML][HTML] Urease-powered nanobots for radionuclide bladder cancer therapy

C Simó, M Serra-Casablancas, AC Hortelao… - Nature …, 2024 - nature.com
Bladder cancer treatment via intravesical drug administration achieves reasonable survival
rates but suffers from low therapeutic efficacy. To address the latter, self-propelled …

Stimuli-responsive functional micro-/nanorobots: a review

Y Zhou, M Ye, C Hu, H Qian, BJ Nelson, X Wang - ACS nano, 2023 - ACS Publications
Stimuli-responsive functional micro-/nanorobots (srFM/Ns) are a class of intelligent, efficient,
and promising microrobots that can react to external stimuli (such as temperature, light …

Biohybrid microalgae robots: design, fabrication, materials, and applications

F Zhang, Z Li, C Chen, H Luan, RH Fang… - Advanced …, 2024 - Wiley Online Library
The integration of microorganisms and engineered artificial components has shown
considerable promise for creating biohybrid microrobots. The unique features of microalgae …

[HTML][HTML] Bacterial therapies at the interface of synthetic biology and nanomedicine

J Hahn, S Ding, J Im, T Harimoto, KW Leong… - Nature Reviews …, 2024 - nature.com
Bacteria are emerging as living drugs to treat a broad range of disease indications.
However, the inherent advantages of these replicating and immunostimulatory therapies …

[HTML][HTML] Construction of intelligent moving micro/nanomotors and their applications in biosensing and disease treatment

Y Guo, D Jing, S Liu, Q Yuan - Theranostics, 2023 - ncbi.nlm.nih.gov
Micro/nanomotors are containers that pass through liquid media and carry cargo. Because
they are tiny, micro/nanomotors exhibit excellent potential for biosensing and disease …