The interplay between viruses and RNAi pathways in insects

BC Bonning, MC Saleh - Annual Review of Entomology, 2021 - annualreviews.org
As an overarching immune mechanism, RNA interference (RNAi) displays pathogen
specificity and memory via different pathways. The small interfering RNA (siRNA) pathway is …

Sensing and signalling viral infection in drosophila

J Schneider, JL Imler - Developmental & Comparative Immunology, 2021 - Elsevier
The fruitfly Drosophila melanogaster is a valuable model to unravel mechanisms of innate
immunity, in particular in the context of viral infections. RNA interference, and more …

[HTML][HTML] lncRNA sensing of a viral suppressor of RNAi activates non-canonical innate immune signaling in Drosophila

L Zhang, W Xu, X Gao, W Li, S Qi, D Guo, OE Ajayi… - Cell host & …, 2020 - cell.com
Antiviral immunity in insects is mediated by the RNA interference (RNAi) pathway. Viruses
evade antiviral RNAi by expressing virulence factors known as viral suppressors of RNAi …

Antimicrobial and anticancer activity of a novel peptide (musterolysin) extracted from slurry of mustard oil refinery industry

SK Mondal, V Perumal, R Das… - ES Food & …, 2022 - espublisher.com
Bacterial infections and cancer has been the most prevalent diseases throughout the World.
The discovery and development of new antibacterial and anticancer agents are critical. If …

Infection defects of RNA and DNA viruses induced by antiviral RNA interference

S Liu, Y Han, WX Li, SW Ding - Microbiology and Molecular …, 2023 - Am Soc Microbiol
Immune recognition of viral genome-derived double-stranded RNA (dsRNA) molecules and
their subsequent processing into small interfering RNAs (siRNAs) in plants, invertebrates …

The capsid protein of Semliki Forest virus antagonizes RNA interference in mammalian cells

Q Qian, H Zhou, T Shu, J Mu, Y Fang, J Xu, T Li… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT RNA interference (RNAi) is a conserved antiviral immune defense in
eukaryotes, and numerous viruses have been found to encode viral suppressors of RNAi …

[HTML][HTML] Parallel evolution and enhanced virulence upon in vivo passage of an RNA virus in Drosophila melanogaster

OM Lezcano, L Fuhrmann, G Ramakrishnan… - Virus …, 2023 - ncbi.nlm.nih.gov
Virus evolution is strongly affected by antagonistic co-evolution of virus and host. Host
immunity positively selects for viruses that evade the immune response, which in turn may …

The importance of AGO 1 and 4 in post-transcriptional gene regulatory function of tRF5-GluCTC, an respiratory syncytial virus-induced tRNA-derived RNA fragment

EJ Choi, J Ren, K Zhang, W Wu, YS Lee, I Lee… - International journal of …, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract
infection in infants, the elderly, and immune-compromised patients. It is also a significant …

RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

Q Shen, YE Wang, M Truong, K Mahadevan… - PLoS …, 2021 - journals.plos.org
Mutations in RanBP2 (also known as Nup358), one of the main components of the
cytoplasmic filaments of the nuclear pore complex, contribute to the overproduction of acute …

Antiviral RNA interference in disease vector (Asian longhorned) ticks

Y Xu, Z Zhong, Y Ren, L Ma, Z Ye, C Gao… - PLoS …, 2021 - journals.plos.org
Disease vectors such as mosquitoes and ticks play a major role in the emergence and re-
emergence of human and animal viral pathogens. Compared to mosquitoes, however, much …