The benefits and risks of testosterone replacement therapy: a review

N Bassil, S Alkaade, JE Morley - Therapeutics and clinical risk …, 2009 - Taylor & Francis
Increased longevity and population aging will increase the number of men with late onset
hypogonadism. It is a common condition, but often underdiagnosed and undertreated. The …

Risks of testosterone-replacement therapy and recommendations for monitoring

EL Rhoden, A Morgentaler - New England Journal of Medicine, 2004 - Mass Medical Soc
Although some reports suggest that testosterone-replacement therapy may provide benefits
for aging men, considerable controversy remains regarding indications for its use. Neither …

[图书][B] Mechanisms of life history evolution: the genetics and physiology of life history traits and trade-offs

T Flatt, A Heyland - 2011 - books.google.com
Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …

Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies

E Hormones… - JNCI: Journal of the …, 2008 - academic.oup.com
Background Sex hormones in serum have been hypothesized to influence the risk of
prostate cancer. We performed a collaborative analysis of the existing worldwide …

Andropause: clinical implications of the decline in serum testosterone levels with aging in men

AM Matsumoto - The Journals of Gerontology Series A …, 2002 - academic.oup.com
T is now well accepted that serum testosterone (T) levels decline progressively with aging in
men (1–5). This decline is associated with alterations in body composition; diminished …

Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels

AM Kenny, KM Prestwood, CA Gruman… - The Journals of …, 2001 - academic.oup.com
Background. A large proportion of men over 65 years of age have bioavailable testosterone
levels below the reference range of young adult men. The impact of this on musculoskeletal …

Is low serum free testosterone a marker for high grade prostate cancer?

MA Hoffman, WC DeWOLF, A Morgentaler - The Journal of urology, 2000 - auajournals.org
Purpose: The association of free and total testosterone with prostate cancer is incompletely
understood. We investigated the relationship of serum free and total testosterone to the …

High‐grade prostate cancer is associated with low serum testosterone levels

G Schatzl, S Madersbacher, T Thurridl… - The …, 2001 - Wiley Online Library
BACKGROUND The aim of this study was to assess whether low serum testosterone levels
in men with newly diagnosed prostate cancer have an association to the endocrine status …

Polycaprolactone–b-poly (ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone

C Allen, J Han, Y Yu, D Maysinger… - Journal of Controlled …, 2000 - Elsevier
Block copolymer micelles formed from copolymers of poly (caprolactone)-b-poly (ethylene
oxide)(PCL-b-PEO) were investigated as a drug delivery vehicle for dihydrotestosterone …

Testosterone for the aging male; current evidence and recommended practice

RD Stanworth, TH Jones - Clinical interventions in aging, 2008 - Taylor & Francis
An international consensus document was recently published and provides guidance on the
diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in men. The …