Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
Risk factors for spontaneous preterm delivery
T Cobo, M Kacerovsky… - International Journal of …, 2020 - Wiley Online Library
Background There is a substantial variation in rates of preterm delivery between different
parts of the world. The understanding of these variations, as well as the biological …
parts of the world. The understanding of these variations, as well as the biological …
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Prevalence and clinical significance of sterile intra‐amniotic inflammation in patients with preterm labor and intact membranes
Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes
Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …
The fetal inflammatory response syndrome
OBJECTIVE: The objective of this study was to determine the frequency and clinical
significance of a systemic inflammatory response as defined by an elevated plasma …
significance of a systemic inflammatory response as defined by an elevated plasma …
Longitudinal changes in serum proinflammatory markers across pregnancy and postpartum: effects of maternal body mass index
LM Christian, K Porter - Cytokine, 2014 - Elsevier
Background The maternal immune system undergoes substantial changes to support
healthy pregnancy. Although obesity is a primary driver of inflammation and predictive of …
healthy pregnancy. Although obesity is a primary driver of inflammation and predictive of …
Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis
GGG Donders, A Vereecken, E Bosmans… - BJOG: an international …, 2002 - Elsevier
OBJECTIVE: To define an entity of abnormal vaginal flora: aerobic vaginitis DESIGN:
Observational study. SETTING: University Hospital Gasthuisberg, Leuven, Belgium …
Observational study. SETTING: University Hospital Gasthuisberg, Leuven, Belgium …