Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

Modified hyaluronic acid based materials for biomedical applications

S Tiwari, P Bahadur - International journal of biological macromolecules, 2019 - Elsevier
Hyaluronic acid (HA) is a high molecular weight, non-sulfated anionic polysaccharide from
glycosamine glycan family. It is a versatile biomaterial that binds to specific cell receptor …

Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

X Yang, W Liu, N Li, M Wang, B Liang, I Ullah… - Biomaterials …, 2017 - pubs.rsc.org
The formation of stable blood clots or hemostasis is essential to prevent major blood loss
and death from excessive bleeding. However, the body's own coagulation process is not …

Chemical modification of hyaluronan and their biomedical applications

V Hintze, M Schnabelrauch, S Rother - Frontiers in Chemistry, 2022 - frontiersin.org
Hyaluronan, the extracellular matrix glycosaminoglycan, is an important structural
component of many tissues playing a critical role in a variety of biological contexts. This …

Tuning the properties of surgical polymeric materials for improved soft-tissue wound closure and healing

Y Chen, M Chai, C Xuan, J Lin, H Yang, C Li… - Progress in Materials …, 2024 - Elsevier
Effective wound management is important, as millions of people suffer traumatic injuries and
surgical operations annually. Proper wound closure is essential for the structural and …

Development and evaluation of performance characteristics of timolol-loaded composite ocular films as potential delivery platforms for treatment of glaucoma

M Tighsazzadeh, JC Mitchell, JS Boateng - International journal of …, 2019 - Elsevier
Thin and erodible polymeric films were developed as potential ocular drug delivery systems
to increase drug retention on the eye with the aim of improving bioavailability and achieving …

Significance of crosslinking approaches in the development of next generation hydrogels for corneal tissue engineering

P Bhattacharjee, M Ahearne - Pharmaceutics, 2021 - mdpi.com
Medical conditions such as trachoma, keratoconus and Fuchs endothelial dystrophy can
damage the cornea, leading to visual deterioration and blindness and necessitating a …

Is hyaluronic acid the perfect excipient for the pharmaceutical need?

D Harrer, ES Armengol, JD Friedl, A Jalil… - International Journal of …, 2021 - Elsevier
Hyaluronic acid has become an interesting and important polymer as an excipient for
pharmaceutical products due to its beneficial properties, like solubility, biocompatibility and …

Novel artificial tears containing cross-linked hyaluronic acid: an in vitro re-epithelialization study

A Fallacara, S Vertuani, G Panozzo, A Pecorelli… - Molecules, 2017 - mdpi.com
Dry eye syndrome is a common disease which can damage the corneal epithelium. It is
treated with eye drops to stimulate tear production and hydrate the corneal surface. The …

Preparation and property evaluation of conductive hydrogel using poly (vinyl alcohol)/polyethylene glycol/graphene oxide for human electrocardiogram acquisition

X Xiao, G Wu, H Zhou, K Qian, J Hu - Polymers, 2017 - mdpi.com
Conductive hydrogel combined with Ag/AgCl electrode is widely used in the acquisition of
bio-signals. However, the high adhesiveness of current commercial hydrogel causes human …