Chalcone: a privileged structure in medicinal chemistry

C Zhuang, W Zhang, C Sheng, W Zhang, C Xing… - Chemical …, 2017 - ACS Publications
Privileged structures have been widely used as an effective template in medicinal chemistry
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …

Organocatalytic carbon–sulfur bond-forming reactions

P Chauhan, S Mahajan, D Enders - Chemical reviews, 2014 - ACS Publications
Carbon− heteroatom bond formations are very important reactions in organic synthesis and
have attracted the interest of many synthetic organic chemists, leading them to develop new …

An organocatalytic Michael-aldol cascade: formal [3+ 2] annulation to construct enantioenriched spirocyclic oxindole derivatives

SW Duan, Y Li, YY Liu, YQ Zou, DQ Shi… - Chemical …, 2012 - pubs.rsc.org
An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched
spirocyclic oxindole derivatives - Chemical Communications (RSC Publishing) …

Hydrogen-bond-mediated cascade reaction involving chalcones: Facile synthesis of enantioenriched trisubstituted tetrahydrothiophenes

JB Ling, Y Su, HL Zhu, GY Wang, PF Xu - Organic letters, 2012 - ACS Publications
A bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction between 1, 4-
dithiane-2, 5-diol and chalcones with a low catalyst loading has been developed …

Colorimetric and ratiometric fluorescent detection of sulfite in water via cationic surfactant-promoted addition of sulfite to α, β-unsaturated ketone

H Tian, J Qian, Q Sun, H Bai, W Zhang - Analytica chimica acta, 2013 - Elsevier
Three fluorescent probes were constructed by incorporating an α, β-unsaturated ketone to a
coumarin fluorophore. The selective addition of sulfite to the alkene of TSP assisted by …

Asymmetric synthesis of trifluoromethyl-substituted 3, 3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1, 3-dipolar cycloaddition reactions

WJ Huang, Q Chen, N Lin, XW Long, WG Pan… - Organic Chemistry …, 2017 - pubs.rsc.org
Unprecedented asymmetric exo′-selective [3+ 2] cycloaddition reactions of CF3-containing
isatin-derived azomethine ylides with methyleneindolinones have been disclosed. Under …

Chalcones, a privileged scaffold: highly versatile molecules in [4+ 2] cycloadditions

S Mastachi‐Loza… - Chemistry–An Asian …, 2022 - Wiley Online Library
Chalcones are aromatic ketones found in nature as the central core of many biological
compounds. They have a wide range of biological activity and are biogenetic precursors of …

N-Heterocyclic carbene-catalyzed sulfa-Michael addition of enals

ZS Cong, YG Li, GF Du, CZ Gu, B Dai… - Chemical …, 2017 - pubs.rsc.org
An efficient N-heterocyclic carbene (NHC) catalyzed sulfa-Michael addition (SMA) between
enals and thiols has been developed. Under the catalysis of 10 mol% stable free carbene …

Organocatalytic Michael/cyclization cascade reactions of 3-isothiocyanato oxindoles with 3-trifluoroethylidene oxindoles: an approach for the synthesis of 3 …

WR Zhu, Q Chen, N Lin, KB Chen, ZW Zhang… - Organic Chemistry …, 2018 - pubs.rsc.org
An efficient asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles
with 3-trifluoroethylidene oxindoles has been revealed. Under bifunctional organocatalysis …

Highly enantioselective organocatalytic Michael addition/cyclization cascade reaction of ylideneoxindoles with isothiocyanato oxindoles: A formal [3+ 2] cycloaddition …

F Tan, HG Cheng, B Feng, YQ Zou… - European Journal of …, 2013 - Wiley Online Library
Abstract A formal [3+ 2] cycloaddition involving the organocatalytic asymmetric Michael
addition/cyclization cascade reaction of ylideneoxindoles with isothiocyanato oxindoles was …