Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

This review presents lower body negative pressure (LBNP) as a unique tool to investigate
the physiology of integrated systemic compensatory responses to altered hemodynamic …

Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

We evaluated postural effects on intracranial pressure (ICP) and cerebral perfusion pressure
[CPP: mean arterial pressure (MAP)− ICP] in neurosurgical patients undergoing 24-h ICP …

Although changes to visual acuity in spaceflight have been observed in some astronauts
since the early days of the space program, the impact to the crew was considered minor …

Multiple transitions between gravity levels will occur during planetary exploration missions.
In reaction to these gravitational transitions, physiological adaptation will be initiated …

During spaceflight, the human cardiovascular system undergoes major changes primarily
related to the effects of decreased gravitational force, or microgravity, on the human body …

Significant progress has been made in the development of countermeasures to attenuate
the negative consequences of prolonged exposure to microgravity on astronauts' bodies …

This review article is a compendium of six individual manuscripts, a Commentary, and an
Executive Summary. This body of work is entitled “The Impact of Sex and Gender on …

Long-duration human spaceflight can lead to changes in both the eye and the brain, which
have been referred to as Spaceflight Associated Neuro-ocular Syndrome (SANS). These …