Membrane electroporation and electropermeabilization: mechanisms and models
Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …
increase in their plasma membrane permeability, allowing transmembrane transport of …
Induced transmembrane voltage and its correlation with electroporation-mediated molecular transport
T Kotnik, G Pucihar, D Miklavčič - The Journal of membrane biology, 2010 - Springer
Exposure of a cell to an electric field results in inducement of a voltage across its membrane
(induced transmembrane voltage, Δ Ψ m) and, for sufficiently strong fields, in a transient …
(induced transmembrane voltage, Δ Ψ m) and, for sufficiently strong fields, in a transient …
Tutorial: Electroporation of cells in complex materials and tissue
L Rems, D Miklavčič - Journal of Applied Physics, 2016 - pubs.aip.org
Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …
biotechnology, and in some environmental applications. Recent applications also include in …
A time-dependent numerical model of transmembrane voltage inducement and electroporation of irregularly shaped cells
G Pucihar, D Miklavcic, T Kotnik - IEEE Transactions on …, 2009 - ieeexplore.ieee.org
We describe a finite-element model of a realistic irregularly shaped biological cell in an
external electric field that allows the calculation of time-dependent changes of the induced …
external electric field that allows the calculation of time-dependent changes of the induced …
Identification of electroporation sites in the complex lipid organization of the plasma membrane
The plasma membrane of a biological cell is a complex assembly of lipids and membrane
proteins, which tightly regulate transmembrane transport. When a cell is exposed to strong …
proteins, which tightly regulate transmembrane transport. When a cell is exposed to strong …
The interplay of excitation and electroporation in nanosecond pulse stimulation
AG Pakhomov, ON Pakhomova - Bioelectrochemistry, 2020 - Elsevier
Conventional electric stimuli of micro-and millisecond duration excite or activate cells at
voltages 10–100 times below the electroporation threshold. This ratio is remarkably different …
voltages 10–100 times below the electroporation threshold. This ratio is remarkably different …
Pulse width and intensity effects of pulsed electric fields on cancerous and normal skin cells
X Rao, S Chen, Y Alfadhl, X Chen, L Sun, L Yu… - Scientific Reports, 2022 - nature.com
Microsecond pulsed electric fields (PEF) have previously been used for various tumour
therapies, such as gene therapy, electrochemotherapy and irreversible electroporation …
therapies, such as gene therapy, electrochemotherapy and irreversible electroporation …
Tissue electroporation as a bioelectric phenomenon: Basic concepts
A Ivorra - Irreversible electroporation, 2010 - Springer
Electroporation is the phenomenon in which cell membrane permeability to ions and
macromolecules is increased by exposing the cell to short (microsecond to millisecond) high …
macromolecules is increased by exposing the cell to short (microsecond to millisecond) high …
High frequency electroporation efficiency is under control of membrane capacitive charging and voltage potential relaxation
The study presents the proof of concept for a possibility to achieve a better electroporation in
the MHz pulse repetition frequency (PRF) region compared to the conventional low …
the MHz pulse repetition frequency (PRF) region compared to the conventional low …
Response of an actin network in vesicles under electric pulses
We study the role of a biomimetic actin network during the application of electric pulses that
induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) …
induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) …