The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

Purpose To update the 2006 American Society of Clinical Oncology guideline on the use of
hematopoietic colony-stimulating factors (CSFs). Methods The American Society of Clinical …

The inaccessibility of living bone marrow (BM) hampers the study of its pathophysiology
under myelotoxic stress induced by drugs, radiation or genetic mutations. Here, we show …

Acute exposure to ionizing radiation induces massive cell death and severe damage to
tissues containing actively proliferating cells, including bone marrow and the gastrointestinal …

The discovery of vitamin E (α-tocopherol) began in 1922 as a vital component required in
reproduction. Today, there are eight naturally occurring vitamin E isoforms, namely α-, β-, γ …

This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …

Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition
requiring effective therapy. Gut microbiota can be manipulated to fight against many …

Significance: Exposure to ionizing radiation (IR) as the result of nuclear accidents or terrorist
attacks is a significant threat and a major medical concern. Hematopoietic stem cell (HSC) …

Purpose To update the 2000 American Society of Clinical Oncology guideline on the use of
hematopoietic colony-stimulating factors (CSF). Update Methodology The Update …