Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …

Epidemiology and Pathophysiology of Multiple Sclerosis : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

The success of clinical trials of selective B‐cell depletion in patients with relapsing multiple
sclerosis (MS) and primary progressive MS has led to a conceptual shift in the …

There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …

Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Regulatory B cells (Bregs) modulate immune responses predominantly, although not
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …

Cytokine production by B cells is important for multiple aspects of immunity. B cell-derived
cytokines, including lymphotoxin, are essential for the ontogenesis, homeostasis and …

B cells are regarded for their capacity to produce antibody. However, recent advances in B
cell biology have capitalized on old findings and demonstrated that B cells also release a …

B cells play a central role in the immune system through the production of antibodies. During
the past two decades, it has become increasingly clear that B cells also have the capacity to …