Copper-catalyzed ortho-acylation of phenols with aryl aldehydes and its application in one-step preparation of xanthones

J Hu, EA Adogla, Y Ju, D Fan, Q Wang - Chemical Communications, 2012 - pubs.rsc.org
In the presence of triphenylphosphine, copper (II) chloride can catalyze an intermolecular
ortho-acylation reaction of phenols with aryl aldehydes. The reaction proceeds smoothly …

Routes to xanthones: an update on the synthetic approaches

C Miguel Goncalves Azevedo… - Current Organic …, 2012 - ingentaconnect.com
Xanthones belong to a class of O-heterocycles which are known for their great variety of
biological/pharmacological activities. The xanthone scaffold can be considered as a …

H‐Bond: Τhe Chemistry‐Biology H‐Bridge

GN Pairas, PG Tsoungas - ChemistrySelect, 2016 - Wiley Online Library
H‐bonding, as a non covalent stabilizing interaction of diverse nature, has a central role in
the structure, function and dynamics of chemical and biological processes, pivotal to …

Recent advances in the synthesis of heterocycles from oximes

E Abele, R Abele - Current Organic Synthesis, 2014 - ingentaconnect.com
This review demonstrates that oximes and their derivatives are valuable starting materials
for the preparation of many classes of heterocyclic compounds. The main group of reactions …

One-step synthesis of xanthones catalyzed by a highly efficient copper-based magnetically recoverable nanocatalyst

CA Menendez, F Nador, G Radivoy, DC Gerbino - Organic letters, 2014 - ACS Publications
A versatile and highly efficient strategy to construct a xanthone skeleton via a ligand-free
intermolecular catalytic coupling of 2-substituted benzaldehydes and a wide range of …

A green nanopalladium-supported catalyst for the microwave-assisted direct synthesis of xanthones

HS Steingruber, P Mendioroz, AS Diez… - Synthesis, 2020 - thieme-connect.com
We report an efficient, selective, rapid and eco-friendly protocol for the one-step synthesis of
a small xanthone library via an intermolecular catalytic coupling from readily available …

Concluding the trilogy: The interaction of 2, 2′‐dihydroxy‐benzophenones and their carbonyl N‐analogues with human glutathione transferase M1‐1 face to face …

ND Georgakis, DA Karagiannopoulos… - Chemical Biology & …, 2017 - Wiley Online Library
A series of 2, 2′‐dihydroxybenzophenones and their carbonyl N‐analogues were studied
as potential inhibitors against human glutathione transferase M1‐1 (hGSTM 1‐1) purified …

Naphtho[1,8-de][1,2]Oxazin-4-ol: Precursor to 1,2,8-Trisubstituted Naphthalenes and 1-Unsubstituted Naphtho[1,2-d]isoxazole 2-Oxide: A Novel Isomerization of the N-Oxide to …

IE Gerontitis, PG Tsoungas, G Varvounis - Molecules, 2023 - mdpi.com
Naphtho [1, 8-de][1, 2] oxazin-4-ol and its acyl or benzyl derivatives ring open to various 2, 8-
dihydroxy-1-naphthonitriles, which, through (de) protection protocols and reduction, afford …

2, 2′-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1

FD Perperopoulou, PG Tsoungas, TN Thireou… - Bioorganic & Medicinal …, 2014 - Elsevier
The MDR-involved human GSTA1-1, an important isoenzyme overexpressed in several
tumors leading to chemotherapeutic-resistant tumour cells, has been targeted by 2, 2 …

Isoenzyme‐and Allozyme‐Specific Inhibitors: 2, 2′‐Dihydroxybenzophenones and Their Carbonyl N‐Analogues that Discriminate between Human Glutathione …

FM Pouliou, TN Thireou, EE Eliopoulos… - Chemical Biology & …, 2015 - Wiley Online Library
The selectivity of certain benzophenones and their carbonyl N‐analogues was investigated
towards the human GSTP 1‐1 allozymes A, B and C involved in MDR. The allozymes were …