Stress exposure, food intake and emotional state

YM Ulrich-Lai, S Fulton, M Wilson, G Petrovich… - Stress, 2015 - Taylor & Francis
This manuscript summarizes the proceedings of the symposium entitled,“Stress, Palatable
Food and Reward”, that was chaired by Drs. Linda Rinaman and Yvonne Ulrich-Lai at the …

[HTML][HTML] The melanocortin system behind the dysfunctional eating behaviors

E Micioni Di Bonaventura, L Botticelli, D Tomassoni… - Nutrients, 2020 - mdpi.com
The dysfunction of melanocortin signaling has been associated with obesity, given the
important role in the regulation of energy homeostasis, food intake, satiety and body weight …

[HTML][HTML] Increased intrinsic and synaptic excitability of hypothalamic POMC neurons underlies chronic stress-induced behavioral deficits

X Fang, Y Chen, J Wang, Z Zhang, Y Bai… - Molecular …, 2023 - nature.com
Chronic stress exposure induces maladaptive behavioral responses and increases
susceptibility to neuropsychiatric conditions. However, specific neuronal populations and …

[HTML][HTML] Neuroendocrine circuits governing energy balance and stress regulation: functional overlap and therapeutic implications

YM Ulrich-Lai, KK Ryan - Cell metabolism, 2014 - cell.com
Significant comorbidities between obesity-related metabolic disease and stress-related
psychological disorders suggest important functional interactions between energy balance …

[HTML][HTML] Interactions with the MC4R rs17782313 variant, mental stress and energy intake and the risk of obesity in Genome Epidemiology Study

S Park, JW Daily, X Zhang, HS Jin, HJ Lee… - Nutrition & metabolism, 2016 - Springer
Background The melanocortin-4 receptor (MC4R) regulates metabolism by modulating
eating behavior and MC4R variants (rs17782313 and rs571312) are associated with obesity …

Hypothalamic dysfunction in obesity and metabolic disorders

S Carmo-Silva, C Cavadas - Obesity and brain function, 2017 - Springer
The hypothalamus is the brain region responsible for the maintenance of energetic
homeostasis. The regulation of this process arises from the ability of the hypothalamus to …

Comparative effects of intranasal neuropeptide Y and HS014 in preventing anxiety and depressive-like behavior elicited by single prolonged stress

EL Sabban, LI Serova, LG Alaluf, M Laukova… - Behavioural Brain …, 2015 - Elsevier
Stress triggered neuropsychiatric disorders are a serious societal problem. Prophylactic
treatment or early intervention has great potential in increasing resilience to traumatic stress …

[HTML][HTML] Central insulin signaling modulates hypothalamus–pituitary–adrenal axis responsiveness

ACN Chong, MC Vogt, AS Hill, JC Brüning… - Molecular metabolism, 2015 - Elsevier
Objective Obesity is often accompanied by hyperactivity of the neuroendocrine stress axis
and has been linked to an increased risk of psychiatric disorders. Insulin is reciprocally …

Energetic stress: The reciprocal relationship between energy availability and the stress response

CS Harrell, CF Gillespie, GN Neigh - Physiology & behavior, 2016 - Elsevier
The worldwide epidemic of metabolic syndromes and the recognized burden of mental
health disorders have driven increased research into the relationship between the two. A …

Pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nucleus of the amygdala induces anxiety via melanocortin receptors

A Iemolo, M Seiglie, A Blasio, P Cottone, V Sabino - Psychopharmacology, 2016 - Springer
Rationale Anxiety disorders are the most common mental disorders in the USA.
Characterized by feelings of uncontrollable apprehension, they are accompanied by …