Alpha‐synuclein in peripheral tissues and body fluids as a biomarker for P arkinson's disease–a systematic review

N Malek, D Swallow, KA Grosset… - Acta Neurologica …, 2014 - Wiley Online Library
Parkinson's disease (PD) is neuropathologically characterized as an alpha‐
synucleinopathy. Alpha‐synuclein‐containing inclusions are stained as L ewy bodies and L …

[HTML][HTML] Diagnostic biomarkers for Parkinson's disease at a glance: where are we?

I Cova, A Priori - Journal of Neural Transmission, 2018 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder whose aetiology remains unclear:
degeneration involves several neurotransmission systems, resulting in a heterogeneous …

Cerebrospinal fluid patterns and the risk of future dementia in early, incident Parkinson disease

DC Bäckström, ME Domellöf, J Linder, B Olsson… - JAMA …, 2015 - jamanetwork.com
Importance Alterations in cerebrospinal fluid (CSF) have been found in Parkinson disease
(PD) and in PD dementia (PDD), but the prognostic importance of such changes is not well …

Proteomic profiling of exosomal proteins for blood-based biomarkers in Parkinson's disease

Y Kitamura, M Kojima, T Kurosawa, R Sasaki… - Neuroscience, 2018 - Elsevier
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder and is characterized by loss of dopaminergic neurons. Biomarkers for tracking …

[HTML][HTML] Neuro-nanotechnology: diagnostic and therapeutic nano-based strategies in applied neuroscience

L Shabani, M Abbasi, Z Azarnew, AM Amani… - Biomedical engineering …, 2023 - Springer
Artificial, de-novo manufactured materials (with controlled nano-sized characteristics) have
been progressively used by neuroscientists during the last several decades. The …

Blood biomarkers with Parkinson's disease clusters and prognosis: the oxford discovery cohort

M Lawton, F Baig, G Toulson, A Morovat… - Movement …, 2020 - Wiley Online Library
Abstract Background Predicting prognosis in Parkinson's disease (PD) has important
implications for individual prognostication and clinical trials design and targeting novel …

Metabolite and peptide levels in plasma and CSF differentiating healthy controls from patients with newly diagnosed Parkinson's disease

M Trupp, P Jonsson, A Öhrfelt… - Journal of …, 2014 - content.iospress.com
Background: Parkinson's disease (PD) is a progressive, multi-focal neurodegenerative
disease for which there is no effective disease modifying treatment. A critical requirement for …

Longitudinal EEG changes correlate with cognitive measure deterioration in Parkinson's disease

JN Caviness, JG Hentz, CM Belden… - Journal of …, 2015 - content.iospress.com
Background: QEEG could provide physiological biomarkers for changes over time in
Parkinson's disease (PD) cognitive decline if they track with longitudinal neuropsychological …

Detection of disease conditions and comorbidities

N Howard - US Patent 10,799,186, 2020 - Google Patents
A new computational approach may provide improved detection of disease conditions and
comorbidities, such as PTSD, Parkinson's, Alzheimer's, depression, etc. For example, in an …

[HTML][HTML] COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015), a global–clinical evaluations, serum biomarkers, genetic studies and …

D Santos-García, P Mir, E Cubo, L Vela… - BMC neurology, 2016 - Springer
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder causing
motor and non-motor symptoms that can affect independence, social adjustment and the …