Algorithmic approaches to protein-protein interaction site prediction
TT Aumentado-Armstrong, B Istrate… - Algorithms for Molecular …, 2015 - Springer
Interaction sites on protein surfaces mediate virtually all biological activities, and their
identification holds promise for disease treatment and drug design. Novel algorithmic …
identification holds promise for disease treatment and drug design. Novel algorithmic …
Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins
In this study, we carried out a comparative analysis between two classical methodologies to
prospect residue contacts in proteins: the traditional cutoff dependent (CD) approach and …
prospect residue contacts in proteins: the traditional cutoff dependent (CD) approach and …
Identification of new sphingomyelinases D in pathogenic fungi and other pathogenic organisms
Sphingomyelinases D (SMases D) or dermonecrotic toxins are well characterized in
Loxosceles spider venoms and have been described in some strains of pathogenic …
Loxosceles spider venoms and have been described in some strains of pathogenic …
Interaction of DisBa01 peptide from Bothrops alternatus venom with BRAF melanoma receptors: Modeling and molecular docking
TS Bialves, LL Bastos, JAA Parra, MN Moysés… - International Journal of …, 2024 - Elsevier
Metastatic melanoma is highly aggressive and challenging, often leading to a grim
prognosis. Its progression is swift, especially when mutations like BRAFV600E continuously …
prognosis. Its progression is swift, especially when mutations like BRAFV600E continuously …
PSAP: protein structure analysis package
B Balamurugan, MNA Roshan… - Journal of Applied …, 2007 - journals.iucr.org
A computing engine, the Protein Structure Analysis Package (PSAP), has been developed to
calculate and display various hidden structural and functional features of three-dimensional …
calculate and display various hidden structural and functional features of three-dimensional …
[HTML][HTML] New mutation in the myocilin gene segregates with juvenile-onset open-angle glaucoma in a Brazilian family
CA Braghini, IAP Neshich, G Neshich, FC Soardi… - Gene, 2013 - Elsevier
Mutations in the myocilin gene (MYOC) account for most cases of autosomal dominant
juvenile-onset open-angle glaucoma (JOAG), an earlier and more severe form of POAG. We …
juvenile-onset open-angle glaucoma (JOAG), an earlier and more severe form of POAG. We …
EPI-peptide designer: a tool for designing peptide ligand libraries based on epitope–paratope interactions
B Viart, C Dias-Lopes, E Kozlova, CFB Oliveira… - …, 2016 - academic.oup.com
Motivation: Antibodies are an important class of biological drugs, but with limitations, such as
inadequate pharmacokinetics, adverse immunogenicity and high production costs. Synthetic …
inadequate pharmacokinetics, adverse immunogenicity and high production costs. Synthetic …
Computational biology in Brazil
G Neshich - PLoS computational biology, 2007 - journals.plos.org
At the request of the PLoS Computational Biology Editor-in-Chief, I agreed to write about
computational biology in Brazil (see author information in Box 1). That meant describing: a) …
computational biology in Brazil (see author information in Box 1). That meant describing: a) …
Flexible mapping of homology onto structure with homolmapper
NC Rockwell, JC Lagarias - Bmc Bioinformatics, 2007 - Springer
Background Over the past decade, a number of tools have emerged for the examination of
homology relationships among protein sequences in a structural context. Most recent …
homology relationships among protein sequences in a structural context. Most recent …
Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests
F Villalta-Romero, L Borro, B Mandic… - Bioorganic & Medicinal …, 2017 - Elsevier
Snakebites represent an important public health problem, with a great number of victims with
permanent sequelae or fatal outcomes, particularly in rural, agriculturally active areas. The …
permanent sequelae or fatal outcomes, particularly in rural, agriculturally active areas. The …