Brain manganese and the balance between essential roles and neurotoxicity

RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Heavy metals exposure and Alzheimer's disease and related dementias

KM Bakulski, YA Seo, RC Hickman… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases

M Chin-Chan, J Navarro-Yepes… - Frontiers in cellular …, 2015 - frontiersin.org
Neurodegenerative diseases including Alzheimer (AD) and Parkinson (PD) have attracted
attention in last decades due to their high incidence worldwide. The etiology of these …

Manganese oxide nanoparticles as MRI contrast agents in tumor multimodal imaging and therapy

X Cai, Q Zhu, Y Zeng, Q Zeng, X Chen… - International journal of …, 2019 - Taylor & Francis
Contrast agents (CAs) play a crucial role in high-quality magnetic resonance imaging (MRI)
applications. At present, as a result of the Gd-based CAs which are associated with renal …

[PDF][PDF] Manganese in drinking-water: background document for development of WHO guidelines for drinking-water quality

World Health Organization - 2004 - apps.who.int
One of the primary goals of WHO and its member states is that “all people, whatever their
stage of development and their social and economic conditions, have the right to have …

Molecular mechanisms underlying neuroinflammation elicited by occupational injuries and toxicants

D Pathak, K Sriram - International Journal of Molecular Sciences, 2023 - mdpi.com
Occupational injuries and toxicant exposures lead to the development of neuroinflammation
by activating distinct mechanistic signaling cascades that ultimately culminate in the …

[HTML][HTML] Advances and prospects of RAFT polymerization-derived nanomaterials in MRI-assisted biomedical applications

W Zhao, C Li, J Chang, H Zhou, D Wang, J Sun… - Progress in Polymer …, 2023 - Elsevier
Magnetic resonance imaging (MRI) is recognized as the most powerful clinical imaging
modality due to its ability to produce detailed three-dimensional anatomical images and high …

Immune-to-brain communication pathways in inflammation-associated sickness and depression

C D'Mello, MG Swain - Inflammation-associated depression: Evidence …, 2017 - Springer
A growing body of evidence now highlights a key role for inflammation in mediating sickness
behaviors and depression. Systemic inflammatory diseases such as rheumatoid arthritis …

Molecular mechanisms of metal toxicity in the pathogenesis of Alzheimer's disease

MT Kabir, MS Uddin, S Zaman, Y Begum… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common form of dementia, which is progressively
affecting elderly people. The dyshomeostasis of biometals and accumulation of toxic metals …

Manganese-based advanced nanoparticles for biomedical applications: future opportunity and challenges

S Haque, S Tripathy, CR Patra - Nanoscale, 2021 - pubs.rsc.org
Nanotechnology is the most promising technology to evolve in the last decade. Recent
research has shown that transition metal nanoparticles especially manganese (Mn)-based …