Small-molecule drug discovery can be viewed as a challenging multidimensional problem in
which various characteristics of compounds—including efficacy, pharmacokinetics and …

Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

The intrinsic limitations of conventional batch synthesis have hindered its applications in
both solving classical problems and exploiting new frontiers. Microfluidic technology offers a …

Micromixers are crucial components within micro biomedical systems. This article presents a
comprehensive review of the main state-of-the art applications of micromixers in biomedical …

Medicinal chemistry plays a fundamental and underlying role in chemical biology,
pharmacology, and medicine to discover safe and efficacious drugs. Small molecule …

Combinatorial approaches to the discovery of new functional molecules are well established
among chemists and biologists, inspired in large measure by the modular composition of …

This paper demonstrates a simple method to fabricate 3D microchannels and
microvasculature at room temperature by direct-writing liquid metal as a sacrificial template …

Digital microfluidics (DMF) has recently emerged as a popular technology for a wide range
of applications. In DMF, nanoliter to microliter droplets containing samples and reagents can …

Applications of microsystems (microreactors) in continuous-flow chemistry have expanded
rapidly over the past two decades, with numerous reports of higher conversions and yields …

Microfluidic circuits are characterized by fluidic channels and chambers with a linear
dimension on the order of tens to hundreds of micrometers. Components of this size enable …