Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …
been a remarkable increase in approved nano-based pharmaceutical products. These novel …
Regulatory aspects on nanomedicines
Nanomedicines have been in the forefront of pharmaceutical research in the last decades,
creating new challenges for research community, industry, and regulators. There is a strong …
creating new challenges for research community, industry, and regulators. There is a strong …
Zero-defect manufacturing the approach for higher manufacturing sustainability in the era of industry 4.0: a position paper
F Psarommatis, J Sousa, JP Mendonça… - International Journal of …, 2022 - Taylor & Francis
For manufacturing companies, quality management is a key feature for increasing the
competitiveness, productivity, profitability, and sustainability of their systems. Quality …
competitiveness, productivity, profitability, and sustainability of their systems. Quality …
Battery-free, wireless, and flexible electrochemical patch for in situ analysis of sweat cortisol via near field communication
Wearable and flexible biosensing devices have been widely developed for in situ
detections. Cortisol is a vital biomarker which plays crucial regulatory role in numerous …
detections. Cortisol is a vital biomarker which plays crucial regulatory role in numerous …
Polymer therapeutics: Top 10 selling pharmaceuticals—What next?
R Duncan - Journal of Controlled release, 2014 - Elsevier
At the time of the first issue of the Journal of Controlled Release (JCR), polymeric drugs,
polymer–drug and protein conjugates and block copolymer micelles carrying bound drugs …
polymer–drug and protein conjugates and block copolymer micelles carrying bound drugs …
Process analytical technology for continuous manufacturing of solid-dosage forms
M Fonteyne, J Vercruysse, F De Leersnyder… - TrAC Trends in …, 2015 - Elsevier
Currently, pharmaceutical production is making the switch from batch processing towards
continuous processing. The quality of intermediate and end products produced by batch …
continuous processing. The quality of intermediate and end products produced by batch …
Advanced drug delivery nanosystems (aDDnSs): a mini-review
C Demetzos, N Pippa - Drug Delivery, 2014 - Taylor & Francis
Significant progress has been made in nanoscale drugs and delivery systems employing
diverse chemical formulations to facilitate the rate of drug delivery and to improve its …
diverse chemical formulations to facilitate the rate of drug delivery and to improve its …
Therapy for the individual: Towards patient integration into the manufacturing and provision of pharmaceuticals
R Govender, S Abrahmsén-Alami, A Larsson… - European Journal of …, 2020 - Elsevier
Individualized therapy with pharmaceutical products aims to elicit predictable and optimized
treatment responses from specific patients. Doing so requires production platforms and …
treatment responses from specific patients. Doing so requires production platforms and …
Independent tailoring of dose and drug release via a modularized product design concept for mass customization
R Govender, S Abrahmsén-Alami, A Larsson, A Borde… - Pharmaceutics, 2020 - mdpi.com
Independent individualization of multiple product attributes, such as dose and drug release,
is a crucial overarching requirement of pharmaceutical products for individualized therapy …
is a crucial overarching requirement of pharmaceutical products for individualized therapy …
Dynamic macrophages: understanding mechanisms of activation as guide to therapy for atherosclerotic vascular disease
JL Decano, M Aikawa - Frontiers in Cardiovascular Medicine, 2018 - frontiersin.org
An emerging theory is that macrophages are heterogenous; an attribute that allows them to
change behavior and execute specific functions in disease processes. This review aims to …
change behavior and execute specific functions in disease processes. This review aims to …