Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

F Farjadian, A Ghasemi, O Gohari, A Roointan… - …, 2019 - Taylor & Francis
There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

Regulatory aspects on nanomedicines

V Sainz, J Conniot, AI Matos, C Peres… - Biochemical and …, 2015 - Elsevier
Nanomedicines have been in the forefront of pharmaceutical research in the last decades,
creating new challenges for research community, industry, and regulators. There is a strong …

Zero-defect manufacturing the approach for higher manufacturing sustainability in the era of industry 4.0: a position paper

F Psarommatis, J Sousa, JP Mendonça… - International Journal of …, 2022 - Taylor & Francis
For manufacturing companies, quality management is a key feature for increasing the
competitiveness, productivity, profitability, and sustainability of their systems. Quality …

Battery-free, wireless, and flexible electrochemical patch for in situ analysis of sweat cortisol via near field communication

C Cheng, X Li, G Xu, Y Lu, SS Low, G Liu, L Zhu… - Biosensors and …, 2021 - Elsevier
Wearable and flexible biosensing devices have been widely developed for in situ
detections. Cortisol is a vital biomarker which plays crucial regulatory role in numerous …

Polymer therapeutics: Top 10 selling pharmaceuticals—What next?

R Duncan - Journal of Controlled release, 2014 - Elsevier
At the time of the first issue of the Journal of Controlled Release (JCR), polymeric drugs,
polymer–drug and protein conjugates and block copolymer micelles carrying bound drugs …

Process analytical technology for continuous manufacturing of solid-dosage forms

M Fonteyne, J Vercruysse, F De Leersnyder… - TrAC Trends in …, 2015 - Elsevier
Currently, pharmaceutical production is making the switch from batch processing towards
continuous processing. The quality of intermediate and end products produced by batch …

Advanced drug delivery nanosystems (aDDnSs): a mini-review

C Demetzos, N Pippa - Drug Delivery, 2014 - Taylor & Francis
Significant progress has been made in nanoscale drugs and delivery systems employing
diverse chemical formulations to facilitate the rate of drug delivery and to improve its …

Therapy for the individual: Towards patient integration into the manufacturing and provision of pharmaceuticals

R Govender, S Abrahmsén-Alami, A Larsson… - European Journal of …, 2020 - Elsevier
Individualized therapy with pharmaceutical products aims to elicit predictable and optimized
treatment responses from specific patients. Doing so requires production platforms and …

Independent tailoring of dose and drug release via a modularized product design concept for mass customization

R Govender, S Abrahmsén-Alami, A Larsson, A Borde… - Pharmaceutics, 2020 - mdpi.com
Independent individualization of multiple product attributes, such as dose and drug release,
is a crucial overarching requirement of pharmaceutical products for individualized therapy …

Dynamic macrophages: understanding mechanisms of activation as guide to therapy for atherosclerotic vascular disease

JL Decano, M Aikawa - Frontiers in Cardiovascular Medicine, 2018 - frontiersin.org
An emerging theory is that macrophages are heterogenous; an attribute that allows them to
change behavior and execute specific functions in disease processes. This review aims to …