Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …

Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating
infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and …

Viral infectious diseases are seriously endangering human health. In the search for effective
antiviral drugs, people have found that polysaccharides have good antiviral activity. As an …

Plant polysaccharides represent a natural source material characterized by high ubiquity,
abundance and biological activities that can be utilised as organic matter in numerous …

Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …

Carbohydrates are the most abundant natural products. Besides their role in metabolism
and as structural building blocks, they are fundamental constituents of every cell surface …

Recently, the studies on the antiviral activities of marine natural products, especially marine
polysaccharides, are attracting more and more attention all over the world. Marine-derived …

Herpes simplex virus type‐1 and type‐2 are highly prevalent human pathogens causing life‐
long infections. The process of infection begins when the virions bind heparan sulfate …

In recent years, many compounds having potent antiviral activity in cell culture have been
detected and some of these compounds are currently undergoing either preclinical or …