The detrimental impact of early life adversities (ELAs; entailing pre-and postnatal
experiences) on the developing brain has been well established. By inducing neural …

Coincident with the opioid epidemic in the United States has been a dramatic increase in the
number of children born with neonatal abstinence syndrome (NAS), a form of withdrawal …

Purpose Exposure to prenatal opioids may adversely impact the developing brain networks.
The aim of this pilot study was to evaluate alterations in amygdalar functional connectivity in …

Brain development is most rapid during the fetal period and the first years of life. This
process can be affected by many in utero factors, such as chemical exposures and maternal …

Background Neonatal abstinence syndrome (NAS) includes an array of symptoms impacting
opioid-exposed newborns (OEN) owing to postnatal withdrawal from in utero substance …

Neuroanatomical and cognitive differences have been documented during childhood
between children with prenatal opioid-and poly-drug exposure and controls in small …

Prenatal opioid exposure (POE) has shown to be a risk factor for adverse long-term
cognitive and behavioral outcomes in offspring. However, the neural mechanisms of these …

The opioid epidemic is an ongoing public health crisis, and children born following prenatal
opioid exposure (POE) have increased risk of long-term cognitive and behavioral sequelae …

Prenatal substance exposure has the potential to impact a variety of domains, with
neurobiological effects that last throughout the lifespan. Different substances may impact the …

Purpose The purpose was to summarize evidence of long‐term outcomes of children, 2
years and older, exposed to opioids in‐utero. Design This was a systematic review. Studies …