There is a growing interest in the targeting of Toll-like receptors (TLRs) for the prevention
and treatment of cancer, rheumatoid arthritis, inflammatory bowel disease and systemic …

Introduction: Sepsis remains a leading cause of death worldwide. Despite years of extensive
research, effective drugs that inhibit the pro-inflammatory effects of lipopolysaccharide (LPS) …

Introduction: The immune response is mediated via two parallel immune components, innate
and adaptive, whose effector functions are highly integrated and coordinated for the …

Abstract Abdominal Aortic Aneurysm (AAA) is a major cause of mortality and morbidity in
men over 65 years of age. Male apolipoprotein E knockout (ApoE−/−) mice infused with …

Background: Toll-like receptors (TLRs) have been recently recognised as primary receptors
in the innate immune system. Apart from initiating a prompt immune response against …

Microbial proteins have recently been found to have more benefits in clinical disease
treatment because of their better-developed strategy and properties than traditional …

Toll 样受体(TLR) 是一类模式识别受体, 通过多种信号传递改善免疫系统功能, 活化NF-κB
信号通路, 调节TNF-α, ILs 和IFN-α 等多种细胞因子分泌, 在天然免疫系统中发挥重要作用 …

During first merogony E. bovis forms large-sized macromeronts containing> 120,000
merozoites. Given thatobligate intracellular replicating coccidians are generally considered …