Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …

Nanomedicines are attractive paradigms to deliver drugs, contrast agents,
immunomodulators, and gene editors for cancer therapy and diagnosis. However, the …

With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with an extremely low
survival rate. New and effective approaches for treatment are therefore urgently needed …

As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Over last decades, most antitumor therapeutic strategies have focused on apoptosis,
however, apoptosis resistance and immunological silence usually led to treatment failure. In …

The first generation of nanomedicine exhibits superior performance in the clinical treatment
of various cancers compared to free conventional anticancer therapeutics. However, poor …

Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …