The permeability barrier is required for terrestrial life and is localized to the stratum corneum,
where extracellular lipid membranes inhibit water movement. The lipids that constitute the …

Biochemistry of chondrotin sulphate• Mechanism of action of chondroitin sulphate‐Effect of
chondroitin sulphate on the chondrocyte‐Effect of chondroitin sulphate on the synovial …

Abstract IL-19, IL-20, IL-22, IL-24, and IL-26 are members of the IL-10 family of cytokines that
have been shown to be up-regulated in psoriatic skin. Contrary to IL-10, these cytokines …

Linoleic acid (18: 2ω6) and α-linolenic acid (18: 3ω3) represent the parent fats of the two
main classes of polyunsaturated fatty acids: the ω-6 (n-6) and the ω-3 (n-3) fatty acids …

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …

Psoriasis is a common inflammatory skin disease of unknown etiology, for which there is no
cure. This heterogeneous, cutaneous, inflammatory disorder is clinically characterized by …

The cause of psoriasis, a common chronic inflammatory skin disease, is not fully understood.
Microarray experiments have been widely used in recent years to identify genes associated …

Psoriasis is a common disease with the population prevalence ranging from 2% to 3%. Its
prevalence in the population is affected by genetic, environmental, viral, infectious …

The epidermis is a very active site of lipid metabolism, and all peroxisome proliferator-
activated receptor (PPAR) and liver X receptor (LXR) isoforms are expressed in the …

The three isotypes of peroxisome proliferator-activated receptors (PPARs), PPARa, β/δ and
γ, are ligand-inducible transcription factors that belong to the nuclear hormone receptor …