The number of patients with end-stage renal disease is continuously increasing worldwide.
The only therapies for these patients are dialysis and organ transplantation, but the latter is …

Adult mammalian skin wounds heal by forming fibrotic scars. We report that full-thickness
injuries of reindeer antler skin (velvet) regenerate, whereas back skin forms fibrotic scar …

Inflammatory skin diseases including atopic dermatitis (AD) and psoriasis (PSO) are
underpinned by dendritic cell (DC)–mediated T cell responses. Currently, the …

Macrophages are a heterogeneous population of cells involved in tissue homeostasis,
inflammation, and cancer. Although macrophages are densely distributed throughout the …

Palmoplantar skin is structurally and functionally unique, but the transcriptional programs
driving this specialization are unclear. Here, we use bulk and single-cell RNA sequencing of …

Dendritic cell (DC) migration to draining lymph nodes (dLNs) is a slow process that is
believed to begin with DCs approaching and entering into afferent lymphatic capillaries …

Microneedles have demonstrated an essential role in transdermal drug delivery strategy.
Attempts to advance this technology focus on the improvement of functionality to realize …

Injuries that heal by fibrosis can compromise organ function and increase patient morbidity.
The oral mucosal barrier has a high regenerative capacity with minimal scarring, but the …

Macroautophagy/autophagy plays a pivotal role in immune regulation. Its significance is
evident in modulation of immune cell differentiation and maturation, physiologically and …

The stratified squamous epithelium (SSE) forms the epidermis of skin (eg, trunk skin,
foreskin, and labia) and the epithelium of type II mucosal tissues (eg, vagina, ectocervix, and …