Role of oxidative stress and neuroinflammation in attention-deficit/hyperactivity disorder

JC Corona - Antioxidants, 2020 - mdpi.com
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder of
childhood. Although abnormalities in several brain regions and disturbances of the …

Pioglitazone enhances brain mitochondrial biogenesis and phase II detoxification capacity in neonatal rats with 6-OHDA-induced unilateral striatal lesions

D Vázquez-González, JC Corona - Frontiers in Neuroscience, 2023 - frontiersin.org
The psychostimulant methylphenidate (MPH) is the first-line pharmacological treatment for
attention-deficit/hyperactivity disorder (ADHD), but has numerous adverse side effects. The …

Neuroprotective properties of minocycline against methylphenidate-induced neurodegeneration: possible role of CREB/BDNF and Akt/GSK3 signaling pathways in rat …

M Motaghinejad, M Motevalian - Neurotoxicity Research, 2022 - Springer
Neurodegeneration is a side effect of methylphenidate (MPH), and minocycline possesses
neuroprotective properties. This study aimed to investigate the neuroprotective effects of …

Saroglitazar, a novel dual PPAR-α/γ agonist, reverses high fat-low protein diet-induced metabolic and cognitive aberrations in C57BL/6J male mice

RN Dharavath, S Arora, KK Kondepudi, M Bishnoi… - Life Sciences, 2021 - Elsevier
Aims Insulin resistance (IR) has become one of the major causative factors for the
pathogenesis of various metabolic and neurometabolic diseases. The sedentary lifestyle in …

[HTML][HTML] No Effects of Decanoic Acid on Locomotor Activity and Antioxidant Defences in an Experimental Animal Model of Attention-Deficit/Hyperactivity Disorder

S Carreón-Trujillo, JC Corona - Journal of Integrative Neuroscience, 2024 - imrpress.com
Background: Medium-chain triglycerides such as decanoic acid (C10), which is one of the
fatty acids that constitute dietary fats, are of substantial interest for their potential therapeutic …

Atomoxetine Decreases Mitochondrial Biogenesis, Fission and Fusion In Human Neuron-like Cells But Does Not Alter Antioxidant Defences

S Carreón-Trujillo, D Vázquez-González… - Cell Biochemistry and …, 2023 - Springer
Atomoxetine (ATX) is a presynaptic norepinephrine transporter (NET) inhibitor widely
prescribed for attention-deficit/hyperactivity disorder (ADHD) due to its low abuse potential …

Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation

NF Silva, FNA do Prado Mascarenhas… - Journal of Chemical …, 2023 - Elsevier
Benzodiazepine (BZD) abuse is a global problem, including pregnant women. For this
population, the drug of choice is usually alprazolam, which acts as a GABAergic agonist and …

Нейровоспаление и его роль в патогенезе синдрома дефицита внимания с гиперактивностью (обзор литературы)

РФ Гасанов, ИВ Макаров… - Обозрение …, 2023 - bekhterevreview.com
Аннотация В статье рассматривается роль воспалительных реакций в формировании
синдрома дефицита внимания с гиперактивностью (СДВГ). На широком и современном …

[HTML][HTML] Neuroinflammation and its role in the pathogenesis of attention deficit hyperactivity disorder (literature review)

RF Gasanov, IV Makarov, DA Emelina… - VM BEKHTEREV …, 2023 - bekhterevreview.com
The article discusses the role of inflammatory reactions in the formation of attention deficit
hyperactivity disorder (ADHD). Based on a wide and modern material, the mechanisms of …

Methylphenidate and Alprazolam Co-Abuse: Drug-DNA Interactions

S Sharma, M Dutt, N Sharma, RN Dharavath, T Kaur - 2020 - preprints.org
Drug abuse is a major issue worldwide. Methylphenidate (MPH) and alprazolam (ALZ) are
commonly prescribed drugs for the treatment of ADHD and anxiety disorders, respectively …