Terminal phenoxy group as a privileged moiety of the drug scaffold—A short review of most recent studies 2013–2022

P Kozyra, M Pitucha - International Journal of Molecular Sciences, 2022 - mdpi.com
The terminal phenoxy group is a moiety of many drugs in use today. Numerous literature
reports indicated its crucial importance for biological activity; thus, it is a privileged scaffold in …

Exploring the potential of isonicotinohydrazide derivatives in N80 steel corrosion control: An integrated approach through synthesis, modeling, and experimentation in …

AA Mansour, MR Al-hadeethi, H Lgaz… - Colloids and Surfaces A …, 2023 - Elsevier
Abstract N80 carbon steel (N80CS) is recognized for its superior mechanical properties and
cost-effectiveness. However, its susceptibility to corrosion, particularly in hydrochloric acid …

Design, synthesis, characterization, docking studies of novel 4-phenyl acrylamide-1, 3-thiazole derivatives as anti-inflammatory and anti-ulcer agents

HM Pallavi, FH Al-Ostoot, VH Kameshwar… - Journal of Molecular …, 2023 - Elsevier
A great extent of nitrogen containing heterocyclic moiety comprising sulfur atom is
recognized as a valuable combination of therapeutics in medicinal chemistry. In particular …

Diosmin: A Daboia russelii venom PLA2s inhibitor-purified, and characterized from Oxalis corniculata L medicinal plant

KS Kiran, VH Kameshwar, KKM Nagaraju… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Oxalis corniculata L is a medicinal plant that belongs to
the Oxalidaceae family. It is a little, slow-growing plant with a frail appearance typically found …

[HTML][HTML] Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio …

NA Alshaye, MK Elgohary, MS Elkotamy… - Molecules, 2024 - mdpi.com
Molecules | Free Full-Text | Design, Synthesis, and Biological Evaluation of Novel Phenoxy
Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological …

[PDF][PDF] Assessment of ADME and in silico characteristics of natural-drugs from turmeric to evaluate significant COX2 inhibition

M Yusuf, SA Khan - Biointerface Res. Appl. Chem, 2022 - biointerfaceresearch.com
Turmeric contains a variety of natural phytoconstituents, effective in reducing the risk of
certain diseases and disorders, for example, heart disease, diabetes, neoplastic, and other …

Synthesis, analgesic, anti-inflammatory, ulcerogenic evaluation, and docking study of (benzoylphenoxy)-N-{5-[2-methylphenyl-6-chlorobenzoxazole]} acetamides as …

MJN Khadri, HA Khamees, S Kouser… - Journal of Molecular …, 2023 - Elsevier
The COX and 5-LOX inhibitors with analgesic and anti-inflammatory effectiveness and very
less gastrointestinal toxicity have been recognized as constructive and sustainable agents …

Design, synthesis and docking studies of novel 4-aminophenol-1, 2, 4-oxadiazole hybrids as apoptosis inducers against triple negative breast cancer cells targeting …

B Dhanalakshmi, BM Anil Kumar… - Journal of …, 2024 - Taylor & Francis
In our study, a series of novel 4-aminophenol benzamide-1, 2, 4-oxadiazole hybrid
analogues have been designed and synthesized by condensing 4-hydroxyphenyl …

Transition metal complexes of N'-(2-cyanoacetyl) nicotinohydrazide: Synthesis, structural and anticancer activity studies

MH Abdel-Rhman, G Samir, MA Hussien, NM Hosny - Polyhedron, 2024 - Elsevier
On reacting the nicotinic hydrazide with 1-cyanoacetyl-3, 5-dimethylpyrazole, a new ligand,
N'-(2-cyanoacetyl) nicotinohydrazide (H 2 L), was produced and characterized using diverse …

An Overview of the Synthetic Routes and Pharmacological Aspects of Pyridine, Isoxazole, Thiazole, and Indole Derivatives

P HM, Zabiulla, SA Khanum - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
Heterocyclic compounds, which are a privileged class of molecules with both natural and
pharmacological value, plays an essential role in drug development. Research interest on …