Cell migration is crucial for physiological and pathological processes such as
morphogenesis, wound repair, immune response and cancer invasion/metastasis. There are …

RAS-related C3 botulinum toxin substrate 1 (Rac. 1) is one of the important members of Rho
GTPases. It is well known that Rac1 is a cytoskeleton regulation protein that regulates cell …

Abstract Introduction DL-3-n-butylphthalide (NBP) and edaravone dexborneol (Eda-Dex) are
two promising reagents for stroke treatment. However, the impacts of NBP and Eda-Dex on …

Neurodegeneration is a condition of the central nervous system (CNS) characterized by loss
of neural structures and function. The most common neurodegenerative disorders (NDDs) …

Alzheimer's disease (AD) is thought to be caused by amyloid-β (Aβ) accumulation in the
central nervous system due to deficient clearance. The aim of the present study was to …

Metastasis is a major cause of death in patients with colorectal cancer (CRC). Cysteine-rich
protein 2 (CSRP2) has been recently implicated in the progression and metastasis of a …

Stroke still ranks as a most lethal disease worldwide. Angiogenesis during the chronic
phase of ischemic stroke can alleviate ischemic injury and attenuate neurological deficit. XQ …

Stroke is a major contributor to global mortality and disability. While reperfusion is essential
for preventing neuronal death in the penumbra, it also triggers cerebral ischemia …

Metastasis is a complex process by which cancer cells escape from the primary tumor to
colonize distant organs. RAC1 is a member of the RHO family of small guanosine …

Background Damaged mitophagy and impaired angiogenesis involve in the pathogenic
development of ischemic stroke. Active fraction of Polyrhachis vicina (Roger)(AFPR) showed …