The diverse clinico-and histopathological features, frequency of transmission and treatment
outcome of Mycobacterium tuberculosis have been associated with several environmental …

Zambia's estimated incidence of all forms of human tuberculosis (TB) is 707/100,000. High
prevalence of bovine tuberculosis (BTB)–infection with Mycobacterium bovis–in cattle and …

Numerous reports have documented isolated transmission events or clonal outbreaks of
multidrug-resistant Mycobacterium tuberculosis strains, but knowledge of their epidemic …

ABSTRACT The Latin American-Mediterranean (LAM) family of Mycobacterium tuberculosis
is believed to be the cause of∼ 15% of tuberculosis cases worldwide. Previously, we …

Streptomycin (STR) is recommended for the management of multidrug-resistant tuberculosis
(MDR-TB). Streptomycin resistance-conferring mutation types and frequency are shown to …

Background The poor peri-urban areas of developing countries with inadequate living
conditions and a high prevalence of HIV infection have been implicated in the increase of …

Background Tuberculosis (TB) is one of the major public health problems in Zambia.
However, information about lineages of M. tuberculosis complex (MTBC) isolates useful for …

Background Mozambique is one of the countries with the highest burden of tuberculosis (TB)
in Sub-Saharan Africa, and information on the predominant genotypes of Mycobacterium …

Objectives The burden of multidrug-resistant tuberculosis (MDR-TB) has been reported to be
increasing in Zambia. The reasons for the increase are still unclear. This study determined …

Induction of host cell autophagy by starvation was shown to enhance lysosomal delivery to
mycobacterial phagosomes, resulting in the restriction of Mycobacterium tuberculosis …